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Literature summary extracted from

  • Bajaj, R.; Park, M.I.; Stauffacher, C.V.; Davidson, A.L.
    Conformational dynamics in the binding-protein-independent mutant of the Escherichia coli maltose transporter, MalG511, and its interaction with maltose binding protein (2018), Biochemistry, 57, 3003-3015 .
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
7.5.2.1 maltose binding protein low levels of maltose binding protein stimulate enzyme activity Escherichia coli

Cloned(Commentary)

EC Number Cloned (Comment) Organism
7.5.2.1 expressed in Escherichia coli AD126 cells Escherichia coli

Protein Variants

EC Number Protein Variants Comment Organism
7.5.2.1 L135F/I154S the binding-protein-independent mutant of Escherichia coli maltose transporter MalFGK2 retains specificity for maltose and shows a high basal ATPase activity in the absence of maltose binding protein Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.5.2.1 maltose binding protein inhibitory above 0.05 mM Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.5.2.1 ATP + H2O + maltose-[maltose-binding protein][side 1] Escherichia coli
-
 ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.5.2.1 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.5.2.1 ATP + H2O + maltose-[maltose-binding protein][side 1]
-
 Escherichia coli ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.5.2.1 MalFGK2
-
 Escherichia coli
7.5.2.1 MalG511 the binding-protein-independent mutant L135F/I154S of Escherichia coli maltose transporter MalFGK2 retains specificity for maltose and shows a high basal ATPase activity in the absence of maltose binding protein Escherichia coli
7.5.2.1 maltose transporter
-
 Escherichia coli