Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Shams, F.; Oldfield, N.J.; Wooldridge, K.G.; Turner, D.P.
    Fructose-1,6-bisphosphate aldolase (FBA)-a conserved glycolytic enzyme with virulence functions in bacteria 'ill met by moonlight (2014), Biochem. Soc. Trans., 42, 1792-1795 .
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.2.13 cell surface
-
 Streptococcus suis 9986
-
4.1.2.13 cytoplasm
-
 Neisseria meningitidis 5737
-
4.1.2.13 cytoplasm
-
 Mycobacterium tuberculosis 5737
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.2.13 D-fructose 1,6-bisphosphate Neisseria meningitidis
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate Mycobacterium tuberculosis
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate Streptococcus suis
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate Streptococcus suis SS9
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.2.13 Mycobacterium tuberculosis
-
-
-
4.1.2.13 Neisseria meningitidis
-
-
-
4.1.2.13 Streptococcus pneumoniae
-
-
-
4.1.2.13 Streptococcus pneumoniae WU2
-
-
-
4.1.2.13 Streptococcus suis
-
-
-
4.1.2.13 Streptococcus suis SS9
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.2.13 D-fructose 1,6-bisphosphate
-
 Neisseria meningitidis glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate
-
 Mycobacterium tuberculosis glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate
-
 Streptococcus suis glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate
-
 Streptococcus suis SS9 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.2.13 FBA
-
 Neisseria meningitidis
4.1.2.13 FBA
-
 Streptococcus pneumoniae
4.1.2.13 FBA
-
 Mycobacterium tuberculosis
4.1.2.13 FBA
-
 Streptococcus suis
4.1.2.13 fructose-1,6-bisphosphate aldolase
-
 Neisseria meningitidis
4.1.2.13 fructose-1,6-bisphosphate aldolase
-
 Streptococcus pneumoniae
4.1.2.13 fructose-1,6-bisphosphate aldolase
-
 Mycobacterium tuberculosis
4.1.2.13 fructose-1,6-bisphosphate aldolase
-
 Streptococcus suis

General Information

EC Number General Information Comment Organism
4.1.2.13 metabolism the enzyme is involved in the Embden-Meyerhof-Parnas glycolytic pathway and in gluconeogenesis Mycobacterium tuberculosis
4.1.2.13 metabolism the enzyme is involved in the Embden-Meyerhof-Parnas glycolytic pathway and in gluconeogenesis Streptococcus suis
4.1.2.13 physiological function the enzyme is required for optimal adhesion to human cells Neisseria meningitidis
4.1.2.13 physiological function conserved glycolytic enzyme with virulence functions in bacteria. It is involved in the Embden-Meyerhof-Parnas (EMP) glycolytic pathway and in gluconeogenesis. Additional it functions beyond its housekeeping role in central metabolism. Fructose-1,6-bisphosphate aldolase is immunogenic in Streptococcus suis SS9 Streptococcus suis
4.1.2.13 physiological function conserved glycolytic enzyme with virulence functions in bacteria. It is involved in the Embden-Meyerhof-Parnas (EMP) glycolytic pathway and in gluconeogenesis. Additional it functions beyond its housekeeping role in central metabolism. The enzyme from Mycobacterium tuberculosis binds human plasminogen Mycobacterium tuberculosis
4.1.2.13 physiological function conserved glycolytic enzyme with virulence functions in bacteria. It is involved in the Embden-Meyerhof-Parnas (EMP) glycolytic pathway and in gluconeogenesis. Additional it functions beyond its housekeeping role in central metabolism. The enzyme from Neisseria meningitidis is dispensable for survival of, but required for optimal adhesion to human cells Neisseria meningitidis
4.1.2.13 physiological function conserved glycolytic enzyme with virulence functions in bacteria. It is involved in the Embden-Meyerhof-Parnas (EMP) glycolytic pathway and in gluconeogenesis. Additional it functions beyond its housekeeping role in central metabolism. The Pneumococcal enzyme is an immunogenic adhesin which binds Flamingo cadherin receptor Streptococcus pneumoniae