EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.2.1.3 | ATP | above 13.3 mM | Plasmodium knowlesi | |
6.2.1.3 | diphosphate | low inhibition of oleoyl-CoA synthesis | Plasmodium knowlesi | |
6.2.1.3 | oleoyl-CoA | inhibition of oleoyl-CoA synthesis | Plasmodium knowlesi |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.2.1.3 | 0.011 | - |
palmitate | - |
Plasmodium knowlesi | |
6.2.1.3 | 0.028 | - |
stearate | - |
Plasmodium knowlesi | |
6.2.1.3 | 0.03 | - |
oleate | - |
Plasmodium knowlesi | |
6.2.1.3 | 0.041 | - |
linoleate | - |
Plasmodium knowlesi | |
6.2.1.3 | 0.048 | - |
CoA | - |
Plasmodium knowlesi | |
6.2.1.3 | 0.059 | - |
arachidonate | - |
Plasmodium knowlesi | |
6.2.1.3 | 0.73 | - |
ATP | - |
Plasmodium knowlesi |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
6.2.1.3 | Mg2+ | required | Plasmodium knowlesi | |
6.2.1.3 | Mg2+ | Km: 1.554 | Plasmodium knowlesi |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.2.1.3 | Plasmodium knowlesi | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
6.2.1.3 | erythrocyte | of Macaca mulatta or Macaca fascicularis infected with Plasmodium knowlesi | Plasmodium knowlesi | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.2.1.3 | ATP + arachidonate + CoA | - |
Plasmodium knowlesi | AMP + diphosphate + arachidonoyl-CoA | - |
? | |
6.2.1.3 | ATP + linoleate + CoA | - |
Plasmodium knowlesi | AMP + diphosphate + linoleoyl-CoA | - |
? | |
6.2.1.3 | ATP + oleate + CoA | - |
Plasmodium knowlesi | AMP + diphosphate + oleoyl-CoA | - |
? | |
6.2.1.3 | ATP + palmitate + CoA | - |
Plasmodium knowlesi | AMP + diphosphate + palmitoyl-CoA | - |
? | |
6.2.1.3 | ATP + stearate + CoA | - |
Plasmodium knowlesi | AMP + diphosphate + stearoyl-CoA | - |
? |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
6.2.1.3 | 45 | - |
half-life of palmitoyl-CoA synthetase activity: 18 min, half-life of oleoyl-CoA synthetase activity: 4 min, half-life of arachidonyl-CoA synthetase activity: 49 min | Plasmodium knowlesi |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
6.2.1.3 | 7.5 | 8.5 | - |
Plasmodium knowlesi |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
6.2.1.3 | 6.5 | 8.8 | 6.5: about 50% of maximal activity, 8.8: about 70% of maximal activity | Plasmodium knowlesi |