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Literature summary extracted from

  • Navone, L.; Macagno, J.P.; Licona-Cassani, C.; Marcellin, E.; Nielsen, L.K.; Gramajo, H.; Rodriguez, E.
    AllR controls the expression of Streptomyces coelicolor allantoin pathway genes (2015), Appl. Environ. Microbiol., 81, 6649-6659 .
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.3.1.22 55
-
 Hydroxypyruvate pH 7.0, 30°C Streptomyces coelicolor

Organism

EC Number Organism UniProt Comment Textmining
5.3.1.22 Streptomyces coelicolor Q9Z596
-
-
5.3.1.22 Streptomyces coelicolor ATCC BAA-471 Q9Z596
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.1.22 Hydroxypyruvate
-
 Streptomyces coelicolor 2-Hydroxy-3-oxopropanoate
-
 ?
5.3.1.22 Hydroxypyruvate
-
 Streptomyces coelicolor ATCC BAA-471 2-Hydroxy-3-oxopropanoate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.3.1.22 hyi
-
 Streptomyces coelicolor
5.3.1.22 SCO6206
-
 Streptomyces coelicolor

Expression

EC Number Organism Comment Expression
5.3.1.22 Streptomyces coelicolor AllR is a negative regulator of the allantoin pathway, binding to the promoter regions of allantoin catabolic genes down

General Information

EC Number General Information Comment Organism
5.3.1.22 physiological function among all genes from the allantoin pathway that are upregulated in the regulator AllR mutant, the Hyi gene encoding a hydroxypyruvate isomerase is responsible of the impairment of antibiotic production Streptomyces coelicolor