Literature summary extracted from

Chien, C.I.; Chen, Y.W.; Wu, Y.H.; Chang, C.Y.; Wang, T.L.; Wang, C.C.
Functional substitution of a eukaryotic glycyl-tRNA synthetase with an evolutionarily unrelated bacterial cognate enzyme (2014), PLoS ONE, 9, e94659 .

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
6.1.1.14	expressed in Saccharomyces cerevisiae grs1-deficient cells	Thermus thermophilus
6.1.1.14	expressed in Saccharomyces cerevisiae grs1-deficient cells	Homo sapiens
6.1.1.14	expressed in Saccharomyces cerevisiae grs1-deficient cells	Arabidopsis thaliana

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
6.1.1.14	cytoplasm	-	Thermus thermophilus	5737	-
6.1.1.14	cytoplasm	-	Homo sapiens	5737	-
6.1.1.14	cytoplasm	-	Saccharomyces cerevisiae	5737	-
6.1.1.14	cytoplasm	-	Arabidopsis thaliana	5737	-
6.1.1.14	mitochondrion	-	Homo sapiens	5739	-
6.1.1.14	mitochondrion	-	Saccharomyces cerevisiae	5739	-
6.1.1.14	mitochondrion	-	Arabidopsis thaliana	5739	-

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
6.1.1.14	ATP + glycine + tRNAGly	Thermus thermophilus	-	AMP + diphosphate + glycyl-tRNAGly	-	?
6.1.1.14	ATP + glycine + tRNAGly	Homo sapiens	-	AMP + diphosphate + glycyl-tRNAGly	-	?
6.1.1.14	ATP + glycine + tRNAGly	Saccharomyces cerevisiae	-	AMP + diphosphate + glycyl-tRNAGly	-	?
6.1.1.14	ATP + glycine + tRNAGly	Arabidopsis thaliana	-	AMP + diphosphate + glycyl-tRNAGly	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
6.1.1.14	Arabidopsis thaliana	-	-	-
6.1.1.14	Homo sapiens	-	-	-
6.1.1.14	Saccharomyces cerevisiae	-	-	-
6.1.1.14	Thermus thermophilus	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6.1.1.14	ATP + glycine + tRNAGly	-	Thermus thermophilus	AMP + diphosphate + glycyl-tRNAGly	-	?
6.1.1.14	ATP + glycine + tRNAGly	-	Homo sapiens	AMP + diphosphate + glycyl-tRNAGly	-	?
6.1.1.14	ATP + glycine + tRNAGly	-	Saccharomyces cerevisiae	AMP + diphosphate + glycyl-tRNAGly	-	?
6.1.1.14	ATP + glycine + tRNAGly	-	Arabidopsis thaliana	AMP + diphosphate + glycyl-tRNAGly	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
6.1.1.14	GARS	-	Thermus thermophilus
6.1.1.14	GARS	-	Homo sapiens
6.1.1.14	GARS	-	Arabidopsis thaliana
6.1.1.14	Glycyl-tRNA synthetase	-	Thermus thermophilus
6.1.1.14	Glycyl-tRNA synthetase	-	Homo sapiens
6.1.1.14	Glycyl-tRNA synthetase	-	Saccharomyces cerevisiae
6.1.1.14	Glycyl-tRNA synthetase	-	Arabidopsis thaliana
6.1.1.14	GlyRS	-	Thermus thermophilus
6.1.1.14	GlyRS	-	Homo sapiens
6.1.1.14	GlyRS	-	Saccharomyces cerevisiae
6.1.1.14	GlyRS	-	Arabidopsis thaliana
6.1.1.14	GRS1	-	Thermus thermophilus
6.1.1.14	GRS1	-	Homo sapiens
6.1.1.14	GRS1	-	Saccharomyces cerevisiae
6.1.1.14	GRS1	-	Arabidopsis thaliana

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
6.1.1.14	ATP	-	Thermus thermophilus
6.1.1.14	ATP	-	Homo sapiens
6.1.1.14	ATP	-	Saccharomyces cerevisiae
6.1.1.14	ATP	-	Arabidopsis thaliana

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Release 2023.1 (January 2023)