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Literature summary extracted from

  • Lv, Z.; Zhang, F.; Pan, Q.; Fu, X.; Jiang, W.; Shen, Q.; Yan, T.; Shi, P.; Lu, X.; Sun, X.; Tang, K.
    Branch pathway blocking in Artemisia annua is a useful method for obtaining high yield artemisinin (2016), Plant Cell Physiol., 57, 588-602 .
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
1.3.1.92 additional information branch pathway blocking in Artemisia annua is a useful method for obtaining high yield artemisinin. In anti-squalene synthase (SQS) transgenic plants, the transcription levels of beta-caryophyllene synthase (CPS), beta-farnesene synthase (BFS), germacrene A synthase (GAS), amorpha-4,11-diene synthase (ADS), amorphadiene 12-hydroxylase (CYP71AV1) and aldehyde dehydrogenase 1 (ALDH1) all increase. Contents of artemisinin and dihydroartemisinic acid are enhanced by 71% and 223%, respectively, while beta-farnesene is raised to 123% compared to control. The mRNA level of artemisinic aldehyde DELTA11(13) reductase (DBR2) does negligibly change in almost all transgenic plants, overview Artemisia annua

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.92 Artemisia annua C5H429
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