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Literature summary extracted from

  • Sales, L.; Ohara, H.; Ohkawa, K.; Saito, T.; Todoroki, Y.; Srilaong, V.; Kondo, S.
    Salt tolerance in apple seedlings is affected by an inhibitor of ABA 8'-hydroxylase CYP707A (2017), J. Plant Growth Regul., 36, 643-650 .
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.14.137 genes CYP707A1 and CYP707A2, quantitative real-time RT-PCR expression analysis Malus domestica

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.14.137 (1E,3R)-1-[4-(4-[[2-(2-butoxyethoxy)ethoxy]methyl]-1H-1,2,3-triazol-1-yl)phenyl]-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol (-)-Abz-E2B Malus domestica
1.14.14.137 (1E,3S)-1-[4-(4-[[2-(2-butoxyethoxy)ethoxy]methyl]-1H-1,2,3-triazol-1-yl)phenyl]-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol (+)-Abz-E2B Malus domestica

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.137 (+)-abscisate + [reduced NADPH-hemoprotein reductase] + O2 Malus domestica
-
 8'-hydroxyabscisate + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.137 Malus domestica F1T0M7 cv. Fuji
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.137 leaf
-
 Malus domestica
-
1.14.14.137 seedling
-
 Malus domestica
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.137 (+)-abscisate + [reduced NADPH-hemoprotein reductase] + O2
-
 Malus domestica 8'-hydroxyabscisate + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.137 ABA 8'-hydroxylase
-
 Malus domestica
1.14.14.137 CYP707A
-
 Malus domestica
1.14.14.137 MdCYP707A
-
 Malus domestica

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.14.137 cytochrome P-450
-
 Malus domestica
1.14.14.137 NADPH-hemoprotein reductase A flavoprotein containing both FMN and FAD. This enzyme catalyses the transfer of electrons from NADPH, an obligatory two-electron donor, to microsomal P-450 monooxygenases, EC 1.14.14._ Malus domestica

General Information

EC Number General Information Comment Organism
1.14.14.137 metabolism hydroxylation at the 8'-position of abscisic acid appears to be the key step of abscisic acid catabolism, and this reaction is catalyzed by ABA 8'-hydroxylase Malus domestica
1.14.14.137 physiological function hydroxylation at the 8'-position of abscisic acid appears to be the key step of abscisic acid catabolism, and this reaction is catalyzed by ABA 8'-hydroxylase Malus domestica