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Literature summary extracted from

  • Qiu, Z.; Deng, Z.; Tan, H.; Zhou, S.; Cao, L.
    Engineering the robustness of Saccharomyces cerevisiae by introducing bifunctional glutathione synthase gene (2015), J. Ind. Microbiol. Biotechnol., 42, 537-542 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.3.2.2 gene gshF, recombinant expression in Saccharomyces cerevisiae strains BY4717 and BY-G from plasmid JMB125 leading to increased levels of glutathione Streptococcus thermophilus
6.3.2.3 gene gshF, recombinant expression in Saccharomyces cerevisiae strains BY4717 and BY-G from plasmid JMB125 leading to increased levels of glutathione Streptococcus thermophilus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.3.2.2 Mg2+ required Streptococcus thermophilus
6.3.2.3 Mg2+ required Streptococcus thermophilus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.2.2 ATP + L-glutamate + L-cysteine Streptococcus thermophilus
-
 ADP + phosphate + gamma-L-glutamyl-L-cysteine
-
 ?
6.3.2.3 ATP + gamma-L-glutamyl-L-cysteine + glycine Streptococcus thermophilus
-
 ADP + phosphate + glutathione
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.2 Streptococcus thermophilus D7P1H2
-
-
6.3.2.3 Streptococcus thermophilus D7P1H2
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.2 ATP + L-glutamate + L-cysteine
-
 Streptococcus thermophilus ADP + phosphate + gamma-L-glutamyl-L-cysteine
-
 ?
6.3.2.3 ATP + gamma-L-glutamyl-L-cysteine + glycine
-
 Streptococcus thermophilus ADP + phosphate + glutathione
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.3.2.2 bifunctional glutathione synthetase
-
 Streptococcus thermophilus
6.3.2.2 bifunctional GSH synthetase
-
 Streptococcus thermophilus
6.3.2.2 GCSGS
-
 Streptococcus thermophilus
6.3.2.2 gshAB gene name, UniProt Streptococcus thermophilus
6.3.2.2 GshF gene name, UniProt Streptococcus thermophilus
6.3.2.3 bifunctional glutathione synthetase
-
 Streptococcus thermophilus
6.3.2.3 bifunctional GSH synthetase
-
 Streptococcus thermophilus
6.3.2.3 GCSGS
-
 Streptococcus thermophilus
6.3.2.3 gshAB gene name, UniProt Streptococcus thermophilus
6.3.2.3 GshF gene name, UniProt Streptococcus thermophilus

Cofactor

EC Number Cofactor Comment Organism Structure
6.3.2.2 ATP
-
 Streptococcus thermophilus
6.3.2.3 ATP
-
 Streptococcus thermophilus