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Literature summary extracted from

  • Xiao, J.; Li, H.; Wen, S.; Hong, W.
    Concentrated biosynthesis of tobramycin by genetically engineered Streptomyces tenebrarius (2014), J. Gen. Appl. Microbiol., 60, 256-261 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.1.2.2 tobramycin + carbamoyl phosphate + ATP + H2O Streptoalloteichus tenebrarius
-
 nebramycin 5' + AMP + diphosphate + phosphate
-
 ?
6.1.2.2 tobramycin + carbamoyl phosphate + ATP + H2O Streptoalloteichus tenebrarius ST316
-
 nebramycin 5' + AMP + diphosphate + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.1.2.2 Streptoalloteichus tenebrarius
-
-
-
6.1.2.2 Streptoalloteichus tenebrarius ST316
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.2.2 tobramycin + carbamoyl phosphate + ATP + H2O
-
 Streptoalloteichus tenebrarius nebramycin 5' + AMP + diphosphate + phosphate
-
 ?
6.1.2.2 tobramycin + carbamoyl phosphate + ATP + H2O
-
 Streptoalloteichus tenebrarius ST316 nebramycin 5' + AMP + diphosphate + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.1.2.2 TacA
-
 Streptoalloteichus tenebrarius
6.1.2.2 TobZ
-
 Streptoalloteichus tenebrarius

Cofactor

EC Number Cofactor Comment Organism Structure
6.1.2.2 ATP
-
 Streptoalloteichus tenebrarius