BRENDA - Enzyme Database

On the prosthetic groups of the NiFe sulfhydrogenase from Pyrococcus furiosus Topology, structure, and temperature-dependent redox chemistry

Silva, P.; De Castro, B.; Hagen, W.; J. Biol. Inorg. Chem. 4, 284-291 (1999)

Data extracted from this reference:

Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
1.12.98.4
Iron
the alpha-subunit carries the NiFe dinuclear center
Pyrococcus furiosus
1.12.98.4
Nickel
the alpha-subunit carries the NiFe dinuclear center
Pyrococcus furiosus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.12.98.4
Pyrococcus furiosus
E7FI44 AND Q8U2E5 AND Q8U2E4 AND E7FHU4
E7FI44: alpha-subunit, Q8U2E5: beta-subunit, Q8U2E4: gamma-subunit, E7FHU4: delta-subunit
-
Purification (Commentary)
EC Number
Commentary
Organism
1.12.98.4
-
Pyrococcus furiosus
Subunits
EC Number
Subunits
Commentary
Organism
1.12.98.4
heterotetramer
alphabetagammadelta hetreotetramer, 1 * 48700 + 1 * 41800 + 33200 + 29600
Pyrococcus furiosus
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.12.98.4
FAD
the gamma-subunit contains one FAD molecule
Pyrococcus furiosus
1.12.98.4
[2Fe-2S]-center
the gamma-subunit contains one 2Fe-2S cluster
Pyrococcus furiosus
1.12.98.4
[4Fe-4S]-center
the beta subunit contains at least two [4Fe-4S] cubanes. The delta-subunit contains three [4Fe-4S] cubanes
Pyrococcus furiosus
1.12.98.4
[Ni-Fe]-center
the alpha-subunit carries the NiFe dinuclear center
Pyrococcus furiosus
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.12.98.4
FAD
the gamma-subunit contains one FAD molecule
Pyrococcus furiosus
1.12.98.4
[2Fe-2S]-center
the gamma-subunit contains one 2Fe-2S cluster
Pyrococcus furiosus
1.12.98.4
[4Fe-4S]-center
the beta subunit contains at least two [4Fe-4S] cubanes. The delta-subunit contains three [4Fe-4S] cubanes
Pyrococcus furiosus
1.12.98.4
[Ni-Fe]-center
the alpha-subunit carries the NiFe dinuclear center
Pyrococcus furiosus
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
1.12.98.4
Iron
the alpha-subunit carries the NiFe dinuclear center
Pyrococcus furiosus
1.12.98.4
Nickel
the alpha-subunit carries the NiFe dinuclear center
Pyrococcus furiosus
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
1.12.98.4
-
Pyrococcus furiosus
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
1.12.98.4
heterotetramer
alphabetagammadelta hetreotetramer, 1 * 48700 + 1 * 41800 + 33200 + 29600
Pyrococcus furiosus