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Literature summary extracted from

  • Jasniewski, A.J.; Engstrom, L.M.; Vu, V.V.; Park, M.H.; Que, L.
    X-ray absorption spectroscopic characterization of the diferric-peroxo intermediate of human deoxyhypusine hydroxylase in the presence of its substrate eIF5a (2016), J. Biol. Inorg. Chem., 21, 605-618 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.99.29 expressed in Escherichia coli BL21(DE3)pLysS cells Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.14.99.29 Fe2+ non-heme diiron enzyme Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.99.29 [eIF5A]-deoxyhypusine + AH2 + O2 Homo sapiens
-
 [eIF5A]-hypusine + A + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.99.29 Homo sapiens Q9BU89
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.14.99.29 GSH-Sepharose resin column chromatography and Superdex 200 gel filtration Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.99.29 [eIF5A]-deoxyhypusine + AH2 + O2
-
 Homo sapiens [eIF5A]-hypusine + A + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.99.29 deoxyhypusine hydroxylase
-
 Homo sapiens
1.14.99.29 DOHH
-
 Homo sapiens