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Literature summary extracted from

  • Saito, S.; Aoki, H.; Ito, A.; Ueno, S.; Wada, T.; Mitsuzuka, K.; Satoh, M.; Arai, Y.; Miyagi, T.
    Human alpha2,3-sialyltransferase (ST3Gal II) is a stage-specific embryonic antigen-4 synthase (2003), J. Biol. Chem., 278, 26474-26479 .
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.2 Homo sapiens Q16842
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.3.2 kidney ST3Gal II mRNA level is higher in renal cell carcinoma than in nontumor kidney tissues Homo sapiens
-
2.4.3.2 renal cell carcinoma cell a high level of ST3Gal II mRNA was detected in all human RCC cell lines except SMKT-R2 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.2 CMP-N-acetyl-beta-neuraminate + ganglioside GA1
-
 Homo sapiens CMP + ganglioside GM1b
-
 ?
2.4.3.2 CMP-N-acetyl-beta-neuraminate + ganglioside Gb5 i.e. beta-D-Gal-(1_>3)-beta-D-GalNAc-(1-3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc Homo sapiens CMP + ganglioside MSGb5
-
 ?
2.4.3.2 CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
-
 Homo sapiens CMP + ganglioside GD1a
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.3.2 ST3Gal II
-
 Homo sapiens

Expression

EC Number Organism Comment Expression
2.4.3.2 Homo sapiens its increased expression level is closely related to renal carcinogenesis up

General Information

EC Number General Information Comment Organism
2.4.3.2 metabolism the enzyme is involved in the synthesis of globopentaosylceramide Homo sapiens