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Literature summary extracted from

  • Basu, M.; Basu, S.; Stoffyn, A.; Stoffyn, P.
    Biosynthesis in vitro of sialyl(alpha 2-3)neolactotetraosylceramide by a sialyltransferase from embryonic chicken brain (1982), J. Biol. Chem., 257, 12765-12769 .
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.3.6 Triton CF-54
-
 Gallus gallus
2.4.3.6 Triton CF-54/X-100
-
 Gallus gallus
2.4.3.6 Triton X-100
-
 Gallus gallus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.3.6 5'-CMP
-
 Gallus gallus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.3.6 0.5
-
 beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide pH 6.4, 37°C Gallus gallus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.3.6 Golgi membrane
-
 Gallus gallus 139
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.6 Gallus gallus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.3.6 partial, using centrifugation in a sucrose gradient Gallus gallus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.3.6 brain 7- to 12-day old embryonic chicken brain Gallus gallus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.6 CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide i.e. neolactotetraosylceramide Gallus gallus CMP + ganglioside LM1
-
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