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Literature summary extracted from

  • Rateb, M.; Yang, D.; Vodanovic-Jankovic, S.; Yu, Z.; Kron, M.; Shen, B.
    Adipostatins A-D from Streptomyces sp. 4875 inhibiting Brugia malayi asparaginyl-tRNA synthetase and killing adult Brugia malayi parasites (2015), J. Antibiot., 68, 540-542 .
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.1.1.22 adipostatin A
-
 Brugia malayi
6.1.1.22 adipostatin B
-
 Brugia malayi
6.1.1.22 adipostatin C
-
 Brugia malayi
6.1.1.22 adipostatin D
-
 Brugia malayi

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.1.1.22 ATP + L-asparagine + tRNAAsn Brugia malayi
-
 AMP + diphosphate + L-asparaginyl-tRNAAsn
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.22 Brugia malayi
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.22 ATP + L-asparagine + tRNAAsn
-
 Brugia malayi AMP + diphosphate + L-asparaginyl-tRNAAsn
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.1.1.22 Asparaginyl-tRNA synthetase
-
 Brugia malayi

Cofactor

EC Number Cofactor Comment Organism Structure
6.1.1.22 ATP
-
 Brugia malayi