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Literature summary extracted from

  • Chai, W.M.; Wei, M.K.; Wang, R.; Deng, R.G.; Zou, Z.R.; Peng, Y.Y.
    Avocado proanthocyanidins as a source of tyrosinase inhibitors structure characterization, inhibitory activity, and mechanism (2015), J. Agric. Food Chem., 63, 7381-7387 .
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.18.1 afzelechin
-
 Agaricus bisporus
1.14.18.1 catechin
-
 Agaricus bisporus
1.14.18.1 epiafzelechin
-
 Agaricus bisporus
1.14.18.1 epicatechin
-
 Agaricus bisporus
1.14.18.1 epigallocatechin
-
 Agaricus bisporus
1.14.18.1 gallocatechin
-
 Agaricus bisporus
1.14.18.1 additional information avocado proanthocyanidins, from Persea americana fruits, are a source of tyrosinase inhibitors, they are reversible and competitive inhibitors, structure-activity relationships, and inhibition mechanism, overview. Ligand structure analysis by mass spectroscopy Agaricus bisporus
1.14.18.1 procyanidin
-
 Agaricus bisporus
1.14.18.1 prodelphindin
-
 Agaricus bisporus
1.14.18.1 propelargonidin
-
 Agaricus bisporus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.14.18.1 Cu2+ a copper-containing enzyme Agaricus bisporus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.18.1 2 L-dopa + O2 Agaricus bisporus
-
 2 dopaquinone + 2 H2O
-
 ?
1.14.18.1 tyrosine + O2 Agaricus bisporus
-
 dopaquinone + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.18.1 Agaricus bisporus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.18.1 commercial preparation
-
 Agaricus bisporus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.18.1 2 L-dopa + O2
-
 Agaricus bisporus 2 dopaquinone + 2 H2O
-
 ?
1.14.18.1 tyrosine + O2
-
 Agaricus bisporus dopaquinone + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.18.1 mushroom tyrosinase
-
 Agaricus bisporus