EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.18.1 | 2,4-dichlorocinnamic acid | - |
Agaricus bisporus | |
1.14.18.1 | 2-chlorocinnamic acid | - |
Agaricus bisporus | |
1.14.18.1 | 2-cyano-4-hydroxycinnamic acid | - |
Agaricus bisporus | |
1.14.18.1 | 4-Aminobenzoic acid | a noncompetitive inhibitor | Agaricus bisporus | |
1.14.18.1 | benzoic acid | competitive inhibition, 45% inhibition of diphenolase activity at 0.7 mM, 42% inhibition of monophenolase activity at 0.7 mM | Agaricus bisporus | |
1.14.18.1 | Cinnamic acid | competitive inhibition, 48% inhibition of diphenolase activity at 1.0 mM, 50% inhibition of monophenolase activity at 1.0 mM | Agaricus bisporus | |
1.14.18.1 | additional information | inhibition mechanism of mono- and diphenolase activities, overview | Agaricus bisporus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.18.1 | additional information | - |
additional information | Michaelis-Menten kinetics | Agaricus bisporus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.14.18.1 | Cu2+ | a copper-containing enzyme | Agaricus bisporus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.18.1 | 2 L-dopa + O2 | Agaricus bisporus | - |
2 dopaquinone + 2 H2O | - |
? | |
1.14.18.1 | tyrosine + O2 | Agaricus bisporus | - |
dopaquinone + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.18.1 | Agaricus bisporus | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
1.14.18.1 | L-tyrosine + O2 = dopaquinone + H2O | reaction mechanism with mono- and diphenols, overview | Agaricus bisporus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.18.1 | commercial preparation | - |
Agaricus bisporus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.18.1 | 2 2-methyl-L-dopa + O2 | - |
Agaricus bisporus | 2 2-methyldopaquinone + 2 H2O | - |
? | |
1.14.18.1 | 2 L-dopa + O2 | - |
Agaricus bisporus | 2 dopaquinone + 2 H2O | - |
? | |
1.14.18.1 | 2-methyl-L-tyrosine + O2 | - |
Agaricus bisporus | 2-methyldopaquinone + H2O | - |
? | |
1.14.18.1 | L-tyrosine + O2 | - |
Agaricus bisporus | dopaquinone + H2O | - |
? | |
1.14.18.1 | tyrosine + O2 | - |
Agaricus bisporus | dopaquinone + H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.18.1 | mushroom tyrosinase | - |
Agaricus bisporus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.18.1 | additional information | - |
additional information | inhibition kinetics of mono- and diphenolase activities, detailed overview | Agaricus bisporus | |
1.14.18.1 | 0.44 | 0.59 | Cinnamic acid | versus different substrates, pH and temperature not specified in the publication | Agaricus bisporus | |
1.14.18.1 | 0.53 | 0.6 | benzoic acid | versus different substrates, pH and temperature not specified in the publication | Agaricus bisporus |