Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Hatano, K.; Miyamoto, Y.; Nonomura, N.; Kaneda, Y.
    Expression of gangliosides, GD1a, and sialyl paragloboside is regulated by NF-kappaB-dependent transcriptional control of alpha2,3-sialyltransferase I, II, and VI in human castration-resistant prostate cancer cells (2011), Int. J. Cancer, 129, 1838-1847 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.3.2 CMP-N-acetyl-beta-neuraminate + ganglioside GM1a Homo sapiens
-
 CMP + ganglioside GD1a
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.2 Homo sapiens Q11201
-
-
2.4.3.2 Homo sapiens Q16842
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.3.2 PC-3 cell
-
 Homo sapiens
-
2.4.3.2 prostate cancer cell constitutive expression level of ST3Gal I in prostate cancer cells and normal prostate epithelium Homo sapiens
-
2.4.3.2 prostate cancer cell constitutive expression level of ST3Gal II in prostate cancer cells and normal prostate epithelium Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.2 CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
-
 Homo sapiens CMP + ganglioside GD1a
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.3.2 ST3GAL1
-
 Homo sapiens
2.4.3.2 ST3GAL2
-
 Homo sapiens

Expression

EC Number Organism Comment Expression
2.4.3.2 Homo sapiens among the five mammalian homologs of the NF-jB family, RelB RNAi most effectively inhibits the expression of ST3Gal I down
2.4.3.2 Homo sapiens among the five mammalian homologs of the NF-jB family, RelB RNAi most effectively inhibits the expression of ST3Gal II down
2.4.3.2 Homo sapiens expression of ST3Gal I is mildly induced by phorbol-12-myristate-13-acetate. The expression of both ST3Gal I reaches to the peak within 12 h. phorbol-12-myristate-13-acetate-induced ST3Gal I expression is inhibited by NF-kappaB decoy oligodeoxynucleotides but not by AP-1 decoy oligodeoxynucleotides up
2.4.3.2 Homo sapiens expression of ST3Gal II is mildly induced by phorbol-12-myristate-13-acetate. The expression of both ST3Gal II reaches to the peak within 12 h. phorbol-12-myristate-13-acetate-induced ST3Gal II expression is inhibited by NF-kappaB decoy oligodeoxynucleotides but not by AP-1 decoy oligodeoxynucleotides up