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Literature summary extracted from

  • Peracaula, R.; Tabares, G.; Lopez-Ferrer, A.; Brossmer, R.; de Bolos, C.; de Llorens, R.
    Role of sialyltransferases involved in the biosynthesis of Lewis antigens in human pancreatic tumour cells (2005), Glycoconj. J., 22, 135-144 .
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.6 Homo sapiens Q11206
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.3.6 adenocarcinoma cell Capan-1 cell, Panc-1 cell, MDAPanc-3 cell, Capan-1 cell. The level of the ST3Gal III transcripts can not be associated with the degree of differentiation of the tumours from which the cell lines are derived Homo sapiens
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2.4.3.6 CAPAN-1 cell
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 Homo sapiens
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2.4.3.6 MDA-Panc-3 cell
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 Homo sapiens
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2.4.3.6 PANC-1 cell
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 Homo sapiens
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2.4.3.6 pancreas normal pancreas has around 40% less quantity of ST3Gal IV transcript compared to the positive tumour cell lines. The level of the ST3Gal III transcripts can not be associated with the degree of differentiation of the tumours from which the cell lines are derived Homo sapiens
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.6 CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->4)-beta-D-GlcNAc-[protein]
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 Homo sapiens CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-[protein]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.3.6 ST3Gal IV
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
2.4.3.6 metabolism involvement in the formation of the sialyl-Lewis antigens Homo sapiens