EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.7.7 | Pyrococcus horikoshii | O57863 and O57861 | O57863: DNA polymerase II small subunit, gene name polB, ordered locus name: PH0123, O57861: DNA polymerase II large subunit, gene name polC, ordered locus name: PH0121 | - |
2.7.7.7 | Pyrococcus horikoshii OT-3 | O57863 and O57861 | O57863: DNA polymerase II small subunit, gene name polB, ordered locus name: PH0123, O57861: DNA polymerase II large subunit, gene name polC, ordered locus name: PH0121 | - |
3.1.99.B1 | Pyrococcus horikoshii | O50123 | - |
- |
3.1.99.B1 | Pyrococcus horikoshii OT-3 | O50123 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.7 | additional information | FEN-1 has both 5'-flap endonuclease and 5'3' exonuclease activities, FEN-1 activity is elevated by the presence of a 1 nucleotide expansion at the 3' end in the upstream primer of substrates called: structures with a 1 nt 3'-flap, which appear to be the most preferable substrates for FEN-1. Serial intermediates with a 1 nt 3'-flap and 5' variable-length flaps are formed by cooperative functioning of Pyrococcus horikoshii FEN-1 with either B or D DNA polymerases | Pyrococcus horikoshii | ? | - |
? | |
2.7.7.7 | additional information | FEN-1 has both 5'-flap endonuclease and 5'3' exonuclease activities, FEN-1 activity is elevated by the presence of a 1 nucleotide expansion at the 3' end in the upstream primer of substrates called: structures with a 1 nt 3'-flap, which appear to be the most preferable substrates for FEN-1. Serial intermediates with a 1 nt 3'-flap and 5' variable-length flaps are formed by cooperative functioning of Pyrococcus horikoshii FEN-1 with either B or D DNA polymerases | Pyrococcus horikoshii OT-3 | ? | - |
? | |
3.1.99.B1 | additional information | FEN-1 has both 5'-flap endonuclease and 5'-3' exonuclease activities, FEN-1 activity is elevated by the presence of a 1 nucleotide expansion at the 3' end in the upstream primer of substrates called: structures with a 1 nt 3'-flap, which appear to be the most preferable substrates for FEN-1. Serial intermediates with a 1 nt 3'-flap and 5' variable-length flaps are formed by cooperative functioning of Pyrococcus horikoshii FEN-1 with either B or D DNA polymerases | Pyrococcus horikoshii | ? | - |
? | |
3.1.99.B1 | additional information | FEN-1 has both 5'-flap endonuclease and 5'-3' exonuclease activities, FEN-1 activity is elevated by the presence of a 1 nucleotide expansion at the 3' end in the upstream primer of substrates called: structures with a 1 nt 3'-flap, which appear to be the most preferable substrates for FEN-1. Serial intermediates with a 1 nt 3'-flap and 5' variable-length flaps are formed by cooperative functioning of Pyrococcus horikoshii FEN-1 with either B or D DNA polymerases | Pyrococcus horikoshii OT-3 | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.7.7 | DNA polymerases D | - |
Pyrococcus horikoshii |
2.7.7.7 | phPol D | - |
Pyrococcus horikoshii |
3.1.99.B1 | FEN-1 | - |
Pyrococcus horikoshii |
3.1.99.B1 | flap endonuclease-1 | - |
Pyrococcus horikoshii |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.1.99.B1 | 60 | - |
assay at | Pyrococcus horikoshii |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.1.99.B1 | 7.5 | - |
assay at | Pyrococcus horikoshii |
EC Number | General Information | Comment | Organism |
---|---|---|---|
3.1.99.B1 | metabolism | plays important roles with DNA polymerases in DNA replication, repair and recombination | Pyrococcus horikoshii |