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Literature summary extracted from

  • Strochlic, T.I.; Stavrides, K.P.; Thomas, S.V.; Nicolas, E.; OReilly, A.M.; Peterson, J.R.
    Ack kinase regulates CTP synthase filaments during Drosophila oogenesis (2014), EMBO Rep., 15, 1184-1191 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
6.3.4.2 Drosophila melanogaster X2JCY2
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.4.2 germ cell ovarian germline cell Drosophila melanogaster
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Synonyms

EC Number Synonyms Comment Organism
6.3.4.2 CTPS
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 Drosophila melanogaster

General Information

EC Number General Information Comment Organism
6.3.4.2 physiological function in ovarian germline cells CTPS filaments are catalytically active and their assembly is regulated by the non-receptor tyrosine kinase DAck. Egg chambers from flies deficient in DAck catalytic activity exhibit disrupted CTPS filament architecture and morphological defects that correlate with reduced fertility. Ovaries from these flies exhibit reduced levels of total RNA Drosophila melanogaster