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Literature summary extracted from

  • Popp, O.; Larraillet, V.; Kettenberger, H.; Gorr, I.H.; Hilger, M.; Lipsmeier, F.; Zeck, A.; Beaucamp, N.
    Molecular polygamy The promiscuity of L-phenylalanyl-tRNA-synthetase triggers misincorporation of meta- and ortho-tyrosine in monoclonal antibodies expressed by Chinese hamster ovary cells (2015), Biotechnol. Bioeng., 112, 1187-1199 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.1.1.20 ATP + L-phenylalanine + tRNAPhe Cricetulus griseus
-
 AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.20 Cricetulus griseus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.1.1.20 CHO cell
-
 Cricetulus griseus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.20 ATP + 2-L-tyrosine + tRNAPhe
-
 Cricetulus griseus AMP + diphosphate + 2-L-tyrosyl-tRNAPhe
-
 ?
6.1.1.20 ATP + 3-L-tyrosine + tRNAPhe
-
 Cricetulus griseus AMP + diphosphate + 3-L--tyrosyl-tRNAPhe
-
 ?
6.1.1.20 ATP + L-leucine + tRNAPhe
-
 Cricetulus griseus AMP + diphosphate + L-leucyl-tRNAPhe
-
 ?
6.1.1.20 ATP + L-phenylalanine + tRNAPhe
-
 Cricetulus griseus AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.1.1.20 Phenylalanine-tRNA synthetase
-
 Cricetulus griseus
6.1.1.20 PheRS
-
 Cricetulus griseus

Cofactor

EC Number Cofactor Comment Organism Structure
6.1.1.20 ATP
-
 Cricetulus griseus