Literature summary extracted from

Wang, W.; Xia, M.X.; Chen, J.; Yuan, R.; Deng, F.N.; Shen, F.F.
Gene expression characteristics and regulation mechanisms of superoxide dismutase and its physiological roles in plants under stress (2016), Biochemistry (Moscow), 81, 465-480 .

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.15.1.1	gene RsrSOD, recombinant expression under the control of the CaMV35S promoter, in Brassica oleracea var. italica via Agrobacterium tumefaciens-mediated transformation. Both gene expression and enzyme activity of SOD increase significantly in transgenic lines when challenged with Hyaloperonospora parasitica, the causal agent of downy mildew. Three lines exhibit high resistance against downy mildew, with disease symptoms restricted completely	Raphanus sativus var. raphanistroides
1.15.1.1	two splicing variants of PthipI-SODC1, presence of two transcripts of PthipI-SODC1, hipI-SODC1b and hipI-SODC1s. hipI-SODC1b is 69 bp longer than hipI-SODC1s due to an alternative splicing event involving an alternative donor splice site in the sixth intron. Transcript analysis	Populus trichocarpa

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
1.15.1.1	chloroplast	-	Glycine max	9507	-
1.15.1.1	chloroplast	-	Arabidopsis thaliana	9507	-
1.15.1.1	chloroplast	-	Nostoc sp. PCC 7120 = FACHB-418	9507	-
1.15.1.1	chloroplast	-	Nicotiana plumbaginifolia	9507	-
1.15.1.1	cytosol	-	Zea mays	5829	-
1.15.1.1	cytosol	-	Rattus norvegicus	5829	-
1.15.1.1	cytosol	-	Arabidopsis thaliana	5829	-
1.15.1.1	cytosol	-	Nicotiana plumbaginifolia	5829	-
1.15.1.1	mitochondrion	-	Zea mays	5739	-
1.15.1.1	mitochondrion	-	Rattus norvegicus	5739	-
1.15.1.1	mitochondrion	-	Nicotiana plumbaginifolia	5739	-

Metals/Ions

EC Number	Metals/Ions	Comment	Organism
1.15.1.1	Cu2+	Cu/Zn-SOD	Zea mays
1.15.1.1	Cu2+	Cu/Zn-SOD	Rattus norvegicus
1.15.1.1	Cu2+	Cu/Zn-SOD	Arabidopsis thaliana
1.15.1.1	Cu2+	Cu/Zn-SOD	Nicotiana plumbaginifolia
1.15.1.1	Fe2+	Fe-SOD	Glycine max
1.15.1.1	Fe2+	Fe-SOD	Arabidopsis thaliana
1.15.1.1	Fe2+	Fe-SOD	Pseudomonas putida
1.15.1.1	Fe2+	Fe-SOD	Rhodobacter capsulatus
1.15.1.1	Fe2+	Fe-SOD	Nostoc sp. PCC 7120 = FACHB-418
1.15.1.1	Fe2+	Fe-SOD	Nicotiana plumbaginifolia
1.15.1.1	Mn2+	a Mn-SOD	Nicotiana plumbaginifolia
1.15.1.1	Mn2+	Mn-SOD	Zea mays
1.15.1.1	Mn2+	Mn-SOD	Pleurotus ostreatus
1.15.1.1	Mn2+	Mn-SOD	Rattus norvegicus
1.15.1.1	Mn2+	Mn-SOD	Raphanus sativus var. raphanistroides
1.15.1.1	Zn2+	Cu/Zn-SOD	Zea mays
1.15.1.1	Zn2+	Cu/Zn-SOD	Rattus norvegicus
1.15.1.1	Zn2+	Cu/Zn-SOD	Arabidopsis thaliana
1.15.1.1	Zn2+	Cu/Zn-SOD	Nicotiana plumbaginifolia

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.
1.15.1.1	2 superoxide + 2 H+	Zea mays	-	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	Nicotiana tabacum	-	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	Glycine max	-	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	Arabidopsis thaliana	-	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	Pleurotus ostreatus	-	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	Populus trichocarpa	-	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	Nicotiana benthamiana	-	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	Rattus norvegicus	-	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	Pseudomonas putida	-	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	Rhodobacter capsulatus	-	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	Nostoc sp. PCC 7120 = FACHB-418	-	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	Nicotiana plumbaginifolia	-	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	Raphanus sativus var. raphanistroides	-	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	Gypsophila oblanceolata	-	O2 + H2O2	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.15.1.1	Arabidopsis thaliana	-	-	-
1.15.1.1	Arabidopsis thaliana	O78310	-	-
1.15.1.1	Arabidopsis thaliana	P24704	-	-
1.15.1.1	Glycine max	-	-	-
1.15.1.1	Gypsophila oblanceolata	-	-	-
1.15.1.1	Nicotiana benthamiana	-	-	-
1.15.1.1	Nicotiana plumbaginifolia	P11796	-	-
1.15.1.1	Nicotiana plumbaginifolia	P22302	-	-
1.15.1.1	Nicotiana plumbaginifolia	P27082	-	-
1.15.1.1	Nicotiana tabacum	-	-	-
1.15.1.1	Nostoc sp. PCC 7120 = FACHB-418	Q8YSZ1	-	-
1.15.1.1	Pleurotus ostreatus	-	-	-
1.15.1.1	Populus trichocarpa	-	-	-
1.15.1.1	Pseudomonas putida	P09223	-	-
1.15.1.1	Raphanus sativus var. raphanistroides	-	-	-
1.15.1.1	Rattus norvegicus	P07632	-	-
1.15.1.1	Rattus norvegicus	P07895	-	-
1.15.1.1	Rhodobacter capsulatus	O30970	-	-
1.15.1.1	Zea mays	-	-	-

Posttranslational Modification

EC Number	Posttranslational Modification	Comment	Organism
1.15.1.1	additional information	posttranscriptional regulation of SODs, overview	Zea mays
1.15.1.1	additional information	posttranscriptional regulation of SODs, overview	Nicotiana tabacum
1.15.1.1	additional information	posttranscriptional regulation of SODs, overview	Glycine max
1.15.1.1	additional information	posttranscriptional regulation of SODs, overview	Arabidopsis thaliana
1.15.1.1	additional information	posttranscriptional regulation of SODs, overview	Pleurotus ostreatus
1.15.1.1	additional information	posttranscriptional regulation of SODs, overview	Nicotiana benthamiana
1.15.1.1	additional information	posttranscriptional regulation of SODs, overview	Rattus norvegicus
1.15.1.1	additional information	posttranscriptional regulation of SODs, overview	Pseudomonas putida
1.15.1.1	additional information	posttranscriptional regulation of SODs, overview	Rhodobacter capsulatus
1.15.1.1	additional information	posttranscriptional regulation of SODs, overview	Nostoc sp. PCC 7120 = FACHB-418
1.15.1.1	additional information	posttranscriptional regulation of SODs, overview	Nicotiana plumbaginifolia
1.15.1.1	additional information	posttranscriptional regulation of SODs, overview	Raphanus sativus var. raphanistroides
1.15.1.1	additional information	posttranscriptional regulation of SODs, overview	Gypsophila oblanceolata

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.15.1.1	fruit body	-	Pleurotus ostreatus	-
1.15.1.1	leaf	during the early stretching of soybean leaves, removing cytokines or growth factors can induce Fe-SOD mRNA accumulation. In contrast, Fe-SOD mRNA accumulation is normal during any other stage by removing cytokines or growth factors. Fe-SOD expression is related to whether the development stage is leaf expansion or not	Glycine max	-
1.15.1.1	additional information	during different developmental stages of Pleurotus ostreatus, the highest expression levels of the Mn-SOD gene appears in the stage of mature fruit bodies, followed by young fruit bodies and vegetative mycelia. The expression of the Mn-SOD gene is developmentally regulated	Pleurotus ostreatus	-
1.15.1.1	additional information	gene sodB gene, encoding Fe-SOD, is expressed highly in logarithmic phase cells but is downregulated in stationaryphase cells, except when the medium is amended with FeCl3 suggesting that downregulation of Pseudomonas putida sodB in stationary phase cells is due to Fe2+ depletion in this phase of growth. Removal of Fe2+ by adding a Fe-chelator decreases the sodB transcript level, even in logarithmicphase cells	Pseudomonas putida	-
1.15.1.1	additional information	the Fe-SOD gene is expressed at low levels in Rhodobacter capsulatus cells grown under anaerobic or semiaerobic conditions, but expression is strongly induced upon exposure of the bacteria to air	Rhodobacter capsulatus	-
1.15.1.1	mycelium	-	Pleurotus ostreatus	-
1.15.1.1	vascular tissue	the splice variant hipI-SODC1b is differentially expressed, being clearly expressed in cambial and xylem, but not phloem, regions	Populus trichocarpa	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.
1.15.1.1	2 superoxide + 2 H+	-	Zea mays	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	-	Nicotiana tabacum	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	-	Glycine max	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	-	Arabidopsis thaliana	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	-	Pleurotus ostreatus	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	-	Populus trichocarpa	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	-	Nicotiana benthamiana	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	-	Rattus norvegicus	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	-	Pseudomonas putida	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	-	Rhodobacter capsulatus	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	-	Nostoc sp. PCC 7120 = FACHB-418	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	-	Nicotiana plumbaginifolia	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	-	Raphanus sativus var. raphanistroides	O2 + H2O2	-	?
1.15.1.1	2 superoxide + 2 H+	-	Gypsophila oblanceolata	O2 + H2O2	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.15.1.1	alr2938	locus name	Nostoc sp. PCC 7120 = FACHB-418
1.15.1.1	CSD1	-	Arabidopsis thaliana
1.15.1.1	CSD2	-	Arabidopsis thaliana
1.15.1.1	Cu/Zn-SOD	-	Zea mays
1.15.1.1	Cu/Zn-SOD	-	Rattus norvegicus
1.15.1.1	Cu/Zn-SOD	-	Arabidopsis thaliana
1.15.1.1	Cu/Zn-SOD	-	Nicotiana plumbaginifolia
1.15.1.1	Fe-SOD	-	Glycine max
1.15.1.1	Fe-SOD	-	Arabidopsis thaliana
1.15.1.1	Fe-SOD	-	Pseudomonas putida
1.15.1.1	Fe-SOD	-	Rhodobacter capsulatus
1.15.1.1	Fe-SOD	-	Nostoc sp. PCC 7120 = FACHB-418
1.15.1.1	Fe-SOD	-	Nicotiana plumbaginifolia
1.15.1.1	high isoelectric point superoxide dismutase	-	Populus trichocarpa
1.15.1.1	Mn-SOD	-	Zea mays
1.15.1.1	Mn-SOD	-	Pleurotus ostreatus
1.15.1.1	Mn-SOD	-	Rattus norvegicus
1.15.1.1	Mn-SOD	-	Nicotiana plumbaginifolia
1.15.1.1	Mn-SOD	-	Raphanus sativus var. raphanistroides
1.15.1.1	PthipI-SODC	-	Populus trichocarpa
1.15.1.1	PthipI-SODC1	-	Populus trichocarpa
1.15.1.1	PthipI-SODC2	-	Populus trichocarpa
1.15.1.1	RsrSOD	-	Raphanus sativus var. raphanistroides
1.15.1.1	sdB	-	Pseudomonas putida
1.15.1.1	sdB	-	Rhodobacter capsulatus
1.15.1.1	SOD	-	Zea mays
1.15.1.1	SOD	-	Nicotiana tabacum
1.15.1.1	SOD	-	Glycine max
1.15.1.1	SOD	-	Arabidopsis thaliana
1.15.1.1	SOD	-	Pleurotus ostreatus
1.15.1.1	SOD	-	Nicotiana benthamiana
1.15.1.1	SOD	-	Rattus norvegicus
1.15.1.1	SOD	-	Pseudomonas putida
1.15.1.1	SOD	-	Rhodobacter capsulatus
1.15.1.1	SOD	-	Nostoc sp. PCC 7120 = FACHB-418
1.15.1.1	SOD	-	Nicotiana plumbaginifolia
1.15.1.1	SOD	-	Raphanus sativus var. raphanistroides
1.15.1.1	SOD	-	Gypsophila oblanceolata
1.15.1.1	SodB	-	Nostoc sp. PCC 7120 = FACHB-418

Expression

EC Number	Organism	Comment	Expression
1.15.1.1	Pseudomonas putida	gene sodB gene, encoding Fe-SOD, is expressed highly in logarithmic phase cells but is downregulated in stationaryphase cells, except when the medium is amended with FeCl3 suggesting that downregulation of Pseudomonas putida sodB in stationary phase cells is due to Fe2+ depletion in this phase of growth. Removal of Fe2+ by adding a Fe-chelator decreases the sodB transcript level, even in logarithmicphase cells	down
1.15.1.1	Nostoc sp. PCC 7120 = FACHB-418	induced overproduction of the CyAbrB transcription factor CalA (cyanobacterial AbrBlike, Alr0946) in the cyanobacterium Nostoc sp. PCC 7120 downregulates the abundance of Fe-SOD, one of two types of SODs in strain PCC 7120. Purified recombinant CalA interacts with the promoter region of alr2938, encoding Fe-SOD, indicating a transcriptional regulation of Fe-SOD by CalA	down
1.15.1.1	Gypsophila oblanceolata	salinity (50 mM NaCl) causes a decrease in activities of SOD during germination. After stress the activity increases in recovered plants. During vegetative growth, the activity of SOD is strongly enhanced and responsible for salt tolerance	down
1.15.1.1	Arabidopsis thaliana	the Arabidopsis thaliana Fe-SOD gene promoter containing the GTACT motif is repressed by Cu2+. Molecular mechanisms of GTACT motif-dependent transcriptional suppression by Cu2+ are conserved in land plants	down
1.15.1.1	Zea mays	effects of abiotic and biotic stresses on SOD expression, overview	additional information
1.15.1.1	Nicotiana tabacum	effects of abiotic and biotic stresses on SOD expression, overview	additional information
1.15.1.1	Arabidopsis thaliana	effects of abiotic and biotic stresses on SOD expression, overview	additional information
1.15.1.1	Pleurotus ostreatus	effects of abiotic and biotic stresses on SOD expression, overview	additional information
1.15.1.1	Populus trichocarpa	effects of abiotic and biotic stresses on SOD expression, overview	additional information
1.15.1.1	Rattus norvegicus	effects of abiotic and biotic stresses on SOD expression, overview	additional information
1.15.1.1	Pseudomonas putida	effects of abiotic and biotic stresses on SOD expression, overview	additional information
1.15.1.1	Rhodobacter capsulatus	effects of abiotic and biotic stresses on SOD expression, overview	additional information
1.15.1.1	Nostoc sp. PCC 7120 = FACHB-418	effects of abiotic and biotic stresses on SOD expression, overview	additional information
1.15.1.1	Nicotiana plumbaginifolia	effects of abiotic and biotic stresses on SOD expression, overview	additional information
1.15.1.1	Raphanus sativus var. raphanistroides	effects of abiotic and biotic stresses on SOD expression, overview	additional information
1.15.1.1	Zea mays	Fe-SODs and Cu/Zn-SODs are constitutively expressed. Effects of abiotic and biotic stresses on SOD expression, overview	additional information
1.15.1.1	Glycine max	Fe-SODs and Cu/Zn-SODs are constitutively expressed. Effects of abiotic and biotic stresses on SOD expression, overview	additional information
1.15.1.1	Nicotiana plumbaginifolia	Fe-SODs and Cu/Zn-SODs are constitutively expressed. Effects of abiotic and biotic stresses on SOD expression, overview	additional information
1.15.1.1	Arabidopsis thaliana	microRNA miR398, conserved in several plant species, targets two of the three Cu/Zn-SODs of Arabidopsis thaliana (CSD1 and CSD2) by triggering cleavage or inhibiting translation of their mRNAs	additional information
1.15.1.1	Nicotiana benthamiana	other transcription factors such as NAC, GRAS, MYB, and C3H are also involved in the regulation of SOD genes. Effects of abiotic and biotic stresses on SOD expression, overview	additional information
1.15.1.1	Arabidopsis thaliana	regulation of the expression of miR398, overview. Effects of abiotic and biotic stresses on SOD expression, overview	additional information
1.15.1.1	Raphanus sativus var. raphanistroides	both gene expression and enzyme activity of recombinant SOD expressed in Brassica oleracea var. italica increase significantly in transgenic lines when challenged with Hyaloperonospora parasitica, the causal agent of downy mildew	up
1.15.1.1	Nicotiana benthamiana	constitutive overexpression of group IId WRKY gene GhWRKY39-1 in Nicotiana benthamiana confers a greater resistance to infection by both the bacterial pathogen Ralstonia solanacearum and the fungal pathogen Rhizoctonia solani. The transgenic plants also exhibit elevated mRNA levels of several pathogenrelated (PR) genes, including PR1c, PR2, and PR4. Moreover, the transgenic plants display enhanced tolerance to salt and oxidative stress and show elevated expression of several oxidationrelated genes encoding SOD, APX, CAT, and glutathioneS-transferase	up
1.15.1.1	Pleurotus ostreatus	expressions of Mn-SOD and Ni-SOD genes are highly induced	up
1.15.1.1	Nicotiana plumbaginifolia	expressions of Mn-SOD and Ni-SOD genes are highly induced	up
1.15.1.1	Zea mays	expressions of Mn-SOD and Ni-SOD genes are highly induced. The expression of the SOD genes from plants is influenced by plant growth stage and growth regulating substances. The effects of the hormone abscisic acid and osmotic stress can induce expression of Cu/Zn-SOD and Mn-SOD genes in maize	up
1.15.1.1	Arabidopsis thaliana	overexpression of yeast transcription factor ACE1 in Arabidopsis thaliana increases the activities of Cu/Zn-SOD, indicating that ACE1 plays an important role in the regulation of SOD gene expression. The Cu/ZnSOD gene is remarkably activated by ginsenoside Rb2 through transcription factor AP2 binding sites and its induction	up
1.15.1.1	Gypsophila oblanceolata	salinity (50 mM NaCl) causes a decrease in activities of SOD during germination. After stress the activity increases in recovered plants. During vegetative growth, the activity of SOD is strongly enhanced and responsible for salt tolerance	up
1.15.1.1	Rhodobacter capsulatus	the FeSOD gene is expressed at low levels in Rhodobacter capsulatus cells grown under anaerobic or semiaerobic conditions, but expression is strongly induced upon exposure of the bacteria to air	up
1.15.1.1	Nicotiana tabacum	transgenic Nicotiana tabacum plants that overexpress a group IIe WRKY gene designated as BdWRKY36 from Brachypodium distachyon show higher SOD, POX, and CAT activity than the wild-type under drought stress. This implies that ROSscavenging systems might be more effective in transgenic than in wild-type plants. Overexpression of the BdWRKY36 gene may function in activation of the antioxidant defense system, which results in transgenic plants suffering less ROS-mediated injury under drought stress	up

General Information

EC Number	General Information	Comment	Organism
1.15.1.1	additional information	distribution, subcellular location, and physicochemical properties of the Mn-, Fe-, Cu/Zn-, and Ni-SODs, and molecular mechanism of regulation of SOD gene expression, overview	Zea mays
1.15.1.1	additional information	distribution, subcellular location, and physicochemical properties of the Mn-, Fe-, Cu/Zn-, and Ni-SODs, and molecular mechanism of regulation of SOD gene expression, overview	Nicotiana tabacum
1.15.1.1	additional information	distribution, subcellular location, and physicochemical properties of the Mn-, Fe-, Cu/Zn-, and Ni-SODs, and molecular mechanism of regulation of SOD gene expression, overview	Glycine max
1.15.1.1	additional information	distribution, subcellular location, and physicochemical properties of the Mn-, Fe-, Cu/Zn-, and Ni-SODs, and molecular mechanism of regulation of SOD gene expression, overview	Arabidopsis thaliana
1.15.1.1	additional information	distribution, subcellular location, and physicochemical properties of the Mn-, Fe-, Cu/Zn-, and Ni-SODs, and molecular mechanism of regulation of SOD gene expression, overview	Pleurotus ostreatus
1.15.1.1	additional information	distribution, subcellular location, and physicochemical properties of the Mn-, Fe-, Cu/Zn-, and Ni-SODs, and molecular mechanism of regulation of SOD gene expression, overview	Populus trichocarpa
1.15.1.1	additional information	distribution, subcellular location, and physicochemical properties of the Mn-, Fe-, Cu/Zn-, and Ni-SODs, and molecular mechanism of regulation of SOD gene expression, overview	Nicotiana benthamiana
1.15.1.1	additional information	distribution, subcellular location, and physicochemical properties of the Mn-, Fe-, Cu/Zn-, and Ni-SODs, and molecular mechanism of regulation of SOD gene expression, overview	Rattus norvegicus
1.15.1.1	additional information	distribution, subcellular location, and physicochemical properties of the Mn-, Fe-, Cu/Zn-, and Ni-SODs, and molecular mechanism of regulation of SOD gene expression, overview	Pseudomonas putida
1.15.1.1	additional information	distribution, subcellular location, and physicochemical properties of the Mn-, Fe-, Cu/Zn-, and Ni-SODs, and molecular mechanism of regulation of SOD gene expression, overview	Rhodobacter capsulatus
1.15.1.1	additional information	distribution, subcellular location, and physicochemical properties of the Mn-, Fe-, Cu/Zn-, and Ni-SODs, and molecular mechanism of regulation of SOD gene expression, overview	Nostoc sp. PCC 7120 = FACHB-418
1.15.1.1	additional information	distribution, subcellular location, and physicochemical properties of the Mn-, Fe-, Cu/Zn-, and Ni-SODs, and molecular mechanism of regulation of SOD gene expression, overview	Nicotiana plumbaginifolia
1.15.1.1	additional information	distribution, subcellular location, and physicochemical properties of the Mn-, Fe-, Cu/Zn-, and Ni-SODs, and molecular mechanism of regulation of SOD gene expression, overview	Raphanus sativus var. raphanistroides
1.15.1.1	additional information	distribution, subcellular location, and physicochemical properties of the Mn-, Fe-, Cu/Zn-, and Ni-SODs, and molecular mechanism of regulation of SOD gene expression, overview	Gypsophila oblanceolata
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen	Pseudomonas putida
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen	Rhodobacter capsulatus
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a central role in protecting plants against the toxic effects of reactive oxygen species generated during normal cellular metabolic activity or as a result of various environmental stresses, regulation mechanisms and functional role(s) during development and in response to biotic or abiotic stresses, overview. During the early stretching of soybean leaves, removing cytokines or growth factors can induce Fe-SOD mRNA accumulation in contrast, Fe-SOD mRNA accumulation is normal during any other stage by removing cytokines or growth factors. Fe-SOD expression is related to whether the development stage is leaf expansion or not	Glycine max
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a central role in protecting plants against the toxic effects of reactive oxygen species generated during normal cellular metabolic activity or as a result of various environmental stresses, regulation mechanisms and functional role(s) during development and in response to biotic or abiotic stresses, overview. The effect of a particular stress on SOD gene expression is likely governed by the subcellular sites at which oxidative stress is generated	Nicotiana tabacum
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a central role in protecting plants against the toxic effects of reactive oxygen species generated during normal cellular metabolic activity or as a result of various environmental stresses, regulation mechanisms and functional role(s) during development and in response to biotic or abiotic stresses, overview. The effect of a particular stress on SOD gene expression is likely governed by the subcellular sites at which oxidative stress is generated	Populus trichocarpa
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a central role in protecting plants against the toxic effects of reactive oxygen species generated during normal cellular metabolic activity or as a result of various environmental stresses, regulation mechanisms and functional role(s) during development and in response to biotic or abiotic stresses, overview. The effect of a particular stress on SOD gene expression is likely governed by the subcellular sites at which oxidative stress is generated	Nicotiana benthamiana
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a central role in protecting plants against the toxic effects of reactive oxygen species generated during normal cellular metabolic activity or as a result of various environmental stresses, regulation mechanisms and functional role(s) during development and in response to biotic or abiotic stresses, overview. The effect of a particular stress on SOD gene expression is likely governed by the subcellular sites at which oxidative stress is generated	Nostoc sp. PCC 7120 = FACHB-418
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a central role in protecting plants against the toxic effects of reactive oxygen species generated during normal cellular metabolic activity or as a result of various environmental stresses, regulation mechanisms and functional role(s) during development and in response to biotic or abiotic stresses, overview. The effect of a particular stress on SOD gene expression is likely governed by the subcellular sites at which oxidative stress is generated	Arabidopsis thaliana
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a central role in protecting plants against the toxic effects of reactive oxygen species generated during normal cellular metabolic activity or as a result of various environmental stresses, regulation mechanisms and functional role(s) during development and in response to biotic or abiotic stresses, overview. The effect of a particular stress on SOD gene expression is likely governed by the subcellular sites at which oxidative stress is generated	Raphanus sativus var. raphanistroides
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a central role in protecting plants against the toxic effects of reactive oxygen species generated during normal cellular metabolic activity or as a result of various environmental stresses, regulation mechanisms and functional role(s) during development and in response to biotic or abiotic stresses, overview. The effect of a particular stress on SOD gene expression is likely governed by the subcellular sites at which oxidative stress is generated	Gypsophila oblanceolata
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a central role in protecting plants against the toxic effects of reactive oxygen species generated during normal cellular metabolic activity or as a result of various environmental stresses, regulation mechanisms and functional role(s) during development and in response to biotic or abiotic stresses, overview. The effect of a particular stress on SOD gene expression is likely governed by the subcellular sites at which oxidative stress is generated. Chloroplastic Fe-SOD responds to increased oxy-radical formation in chloroplasts	Nicotiana plumbaginifolia
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a central role in protecting plants against the toxic effects of reactive oxygen species generated during normal cellular metabolic activity or as a result of various environmental stresses, regulation mechanisms and functional role(s) during development and in response to biotic or abiotic stresses, overview. The effect of a particular stress on SOD gene expression is likely governed by the subcellular sites at which oxidative stress is generated. Cytosolic Cu/Zn-SOD responds to increased oxy-radical formation in the cytosol	Nicotiana plumbaginifolia
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a central role in protecting plants against the toxic effects of reactive oxygen species generated during normal cellular metabolic activity or as a result of various environmental stresses, regulation mechanisms and functional role(s) during development and in response to biotic or abiotic stresses, overview. The effect of a particular stress on SOD gene expression is likely governed by the subcellular sites at which oxidative stress is generated. Mitochondrial Mn-SOD responds to increased oxy-radical formation in mitochondria. Posttranscriptional regulation of SODs, overview	Nicotiana plumbaginifolia
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a central role in protecting plants against the toxic effects of reactive oxygen species generated during normal cellular metabolic activity or as a result of various environmental stresses, regulation mechanisms and functional role(s) during development and in response to biotic or abiotic stresses, overview. The effect of a particular stress on SOD gene expression is likely governed by the subcellular sites at which oxidative stress is generated. Molecular mechanisms of GTACT motif-dependent transcriptional suppression by Cu2+ are conserved in land plants	Arabidopsis thaliana
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a central role in protecting plants against the toxic effects of reactive oxygen species generated during normal cellular metabolic activity or as a result of various environmental stresses, regulation mechanisms and functional role(s) during development and in response to biotic or abiotic stresses, overview. The expression of the Mn-SOD gene is developmentally regulated	Zea mays
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a central role in protecting plants against the toxic effects of reactive oxygen species generated during normal cellular metabolic activity or as a result of various environmental stresses, regulation mechanisms and functional role(s) during development and in response to biotic or abiotic stresses, overview. The expression of the Mn-SOD gene is developmentally regulated	Pleurotus ostreatus
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen. The expression of the SOD genes from animals is related to hormone levels and cytokines in the body. A study suggested that removal of estradiol by ovariectomy decreases the activity of Cu/Zn-SOD and Mn-SOD in the intra-abdominal tissue of female rats compared with rats treated with ovariectomy but with added estradiol. In addition, a variety of cytokines such as growth factor, tumor necrosis factor, and interleukin regulate response to oxidative stress via regulation of SOD expression	Rattus norvegicus
1.15.1.1	physiological function	superoxide dismutases (SODs) are key enzymes functioning as the first line of antioxidant defense by virtue of the ability to convert highly reactive superoxide radicals to hydrogen peroxide and molecular oxygen. The expression of the SOD genes from animals is related to hormone levels and cytokines in the body. A study suggested that removal of estradiol by ovariectomy decreases the activity of Cu/Zn-SOD and Mn-SOD in the intra-abdominal tissue of female rats compared with rats treated with ovariectomy but with added estradiol. In addition, a variety of cytokines such as growthfactor, tumor necrosis factor, and interleukin regulate response to oxidative stress via regulation of SOD expression	Rattus norvegicus