EC Number | Cloned (Comment) | Organism |
---|---|---|
1.14.19.3 | gene d6-des, DNA and amino acid sequence determination and analysis, sequence comparisons | Echium amoenum |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.19.3 | alpha-linolenoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ | Echium amoenum | - |
stearidonoyl-CoA + 2 ferricytochrome b5 + 2 H2O | - |
? | |
1.14.19.3 | linoleoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ | Echium amoenum | - |
gamma-linolenoyl-CoA + 2 ferricytochrome b5 + 2 H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.19.3 | Echium amoenum | D2KP14 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.19.3 | seed | - |
Echium amoenum | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.19.3 | alpha-linolenoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ | - |
Echium amoenum | stearidonoyl-CoA + 2 ferricytochrome b5 + 2 H2O | - |
? | |
1.14.19.3 | linoleoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ | - |
Echium amoenum | gamma-linolenoyl-CoA + 2 ferricytochrome b5 + 2 H2O | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.14.19.3 | More | secondary structure of the enzyme deduced from its primary structure using computational simulation | Echium amoenum |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.19.3 | d6-des | - |
Echium amoenum |
1.14.19.3 | D6Des | - |
Echium amoenum |
1.14.19.3 | DELTA-6 desaturase | - |
Echium amoenum |
1.14.19.3 | EaD6DES | - |
Echium amoenum |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.19.3 | cytochrome b5 | the enzyme contains a cytochrome b5 domain and three conserved histidine-rich motifs | Echium amoenum |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.14.19.3 | evolution | weak activity and different secondary structure of delta-6 desaturase (D6DES) in Echium amoenum compared with D6DESs of other species | Echium amoenum |
1.14.19.3 | additional information | analysis of functional sites and substrate binding motifs of D6DES enzyme, overview | Echium amoenum |
1.14.19.3 | physiological function | D6DES enzyme is responsible for converting linoleic acid and alpha-linolenic acid to gamma-linolenoic acid and stearidonic acid | Echium amoenum |