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Literature summary extracted from

  • Green, T.; Chen, X.; Ryan, S.; Asch, A.S.; Ruiz-Echevarria, M.J.
    TMEFF2 and SARDH cooperate to modulate one-carbon metabolism and invasion of prostate cancer cells (2013), Prostate, 73, 1561-1575 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.8.3 sarcosine + H2O + electron-transfer flavoprotein Homo sapiens
-
 glycine + formaldehyde + reduced electron-transfer flavoprotein
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.5.8.3 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.8.3 22Rv1 cell
-
 Homo sapiens
-
1.5.8.3 LNCaP cell
-
 Homo sapiens
-
1.5.8.3 prostate cancer cell
-
 Homo sapiens
-
1.5.8.3 RWPE-1 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.8.3 sarcosine + H2O + electron-transfer flavoprotein
-
 Homo sapiens glycine + formaldehyde + reduced electron-transfer flavoprotein
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.5.8.3 SARDH
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
1.5.8.3 malfunction reducing the expression of the enzyme promotes localization of TMEFF2 to the cytoskeleton and also results in increased cellular invasion in tumorigenesis Homo sapiens