Literature summary extracted from

Edge, A.; Qu, Y.; Easson, M.L.A.E.; Thamm, A.M.K.; Kim, K.H.; De Luca, V.
A tabersonine 3-reductase Catharanthus roseus mutant accumulates vindoline pathway intermediates (2018), Planta, 247, 155-169 .

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.1.99.41	expressed in Escherichia coli BL21-(DE3) cells	Catharanthus roseus

Protein Variants

EC Number	Protein Variants	Comment	Organism
1.1.99.41	H189Y	the mutation diminishes the activity of the enzyme by 95%	Catharanthus roseus
1.1.99.41	T305T	inactive	Catharanthus roseus

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.99.41	Catharanthus roseus	A0A161CAI1	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.1.99.41	Ni-NTA column chromatography	Catharanthus roseus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.1.99.41	leaf	-	Catharanthus roseus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.99.41	16-methoxytabersonine + NADPH + H+	-	Catharanthus roseus	3-hydroxy-16-methoxy-2,3-dihydrotabersonine	-	?
1.1.99.41	tabersonine + NADPH + H+	-	Catharanthus roseus	2,3-dihydro-3-hydroxytabersonine + NADP+	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.1.99.41	T3R	-	Catharanthus roseus
1.1.99.41	tabersonine 3-reductas	-	Catharanthus roseus

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Release 2023.1 (January 2023)