Literature summary extracted from

Zerbe, P.; Hamberger, B.; Yuen, M.; Chiang, A.; Sandhu, H.; Madilao, L.; Nguyen, A.; Hamberger, B.; Bach, S.; Bohlmann, J.
Gene discovery of modular diterpene metabolism in nonmodel systems (2013), Plant Physiol., 162, 1073-1091 .

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.2.3.190	Grindelia hirsutula	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.2.3.190	(13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate	-	Grindelia hirsutula	manoyl oxide + diphosphate	-	?
4.2.3.190	additional information	reaction proceeds via cleavage of the diphosphate group of LPP and subsequent heterocyclic ring closure including the hydroxyl group at C-8	Grindelia hirsutula	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
4.2.3.190	TPS6	-	Grindelia hirsutula

General Information

EC Number	General Information	Comment	Organism
4.2.3.190	physiological function	combination of TPS6 with TPS1 in in vitro and in vivo assays results in formation of manoyl oxide with only traces of epi-manoyl oxide. TPS6 forms abietadiene when coupled with ent-CPS	Grindelia hirsutula

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Release 2023.1 (January 2023)