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Literature summary extracted from

  • Bak, S.; Tax, F.; Feldmann, K.; Galbraith, D.; Feyereisen, R.
    CYP83B1, a cytochrome P450 at the metabolic branch point in auxin and indole glucosinolate biosynthesis in Arabidopsis (2001), Plant Cell, 13, 101-111 .
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.14.45 tryptamine competitive Arabidopsis thaliana

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.14.14.45 0.003
-
indole-3-acetaldoxime pH 7.6, 28°C Arabidopsis thaliana

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.45 Arabidopsis thaliana O65782
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.45 indole-3-acetaldoxime + O2 + glutathione + [reduced NADPH-hemoprotein reductase]
-
Arabidopsis thaliana 1-aci-nitro-2-indolyl-ethane + H2O + [oxidized NADPH-hemoprotein reductase]
-
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Synonyms

EC Number Synonyms Comment Organism
1.14.14.45 CYP83B1
-
Arabidopsis thaliana
1.14.14.45 cytochrome P450 83B1
-
Arabidopsis thaliana

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.14.14.45 53
-
indole-3-acetaldoxime pH 7.6, 28°C Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.14.45 cytochrome P450
-
Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
1.14.14.45 physiological function inactivation of CYP83B1 leads to plants with a phenotype that suggests severe auxin overproduction, whereas CYP83B1 overexpression leads to loss of apical dominance typical of auxin deficit Arabidopsis thaliana