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Literature summary extracted from

  • Liu, C.L.; Watson, A.M.; Place, A.R.; Jagus, R.
    Taurine biosynthesis in a fish liver cell line (ZFL) adapted to a serum-free medium (2017), Mar. Drugs, 15, 147-161 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.13.11.19 relative expression level determination in cells grown in taurin-free or taurine-containing medium, overview Danio rerio

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.13.11.19 2-aminoethanethiol + O2 Danio rerio
-
 hypotaurine
-
 ?
1.13.11.19 2-aminoethanethiol + O2 Danio rerio ATCC CRL-2643
-
 hypotaurine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.19 Danio rerio
-
-
-
1.13.11.19 Danio rerio ATCC CRL-2643
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.19 cell culture grown in taurin-free or taurine-containing medium Danio rerio
-
1.13.11.19 hepatocyte
-
 Danio rerio
-
1.13.11.19 liver
-
 Danio rerio
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.19 2-aminoethanethiol + O2
-
 Danio rerio hypotaurine
-
 ?
1.13.11.19 2-aminoethanethiol + O2
-
 Danio rerio ATCC CRL-2643 hypotaurine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.13.11.19 2-aminoethanethiol dioxygenase
-
 Danio rerio
1.13.11.19 ADO
-
 Danio rerio

Expression

EC Number Organism Comment Expression
1.13.11.19 Danio rerio addition of taurine to cells grown in taurine-free medium has little effect on transcript levels of the biosynthetic pathway genes for cysteine dioxygenase (CDO), cysteine sulfinate decarboxylase (CSAD), or cysteamine dioxygenase (ADO). In contrast, supplementation with taurine causes a 30% reduction in transcript levels of the taurine transporter, TauT additional information

General Information

EC Number General Information Comment Organism
1.13.11.19 metabolism the enzyme is involved in the taurine biosynthetic pathway. addition of taurine to cells grown in taurine-free medium has little effect on transcript levels of the biosynthetic pathway genes for cysteine dioxygenase (CDO), cysteine sulfinate decarboxylase (CSAD), or cysteamine dioxygenase (ADO). In contrast, supplementation with taurine causes a 30% reduction in transcript levels of the taurine transporter, TauT. Hypotaurine can be produced via of cysteamine, the end product of coenzyme A degradation, via oxidation by 2-aminoethanethiol dioxygenase (ADO). Taurine biosynthetic pathway from methionine?derived cysteine, overview Danio rerio