Any feedback?
Literature summary extracted from
- Distinct enzyme-substrate interactions revealed by two dimensional kinetic comparison between dehaloperoxidase-hemoglobin and horseradish peroxidase (2015), J. Phys. Chem. B, 119, 12828-12837 .
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.11.1.7 | 2,4,6-tribromophenol | substrate inhibition at high concentration due to the internal binding at the distal pocket of DHP; substrate inhibition at high concentration due to the internal binding at the distal pocket of DHP | Amphitrite ornata |  |
| 1.11.1.7 | 2,4,6-Trichlorophenol | substrate inhibition at high concentration due to the internal binding at the distal pocket of DHP; substrate inhibition at high concentration due to the internal binding at the distal pocket of DHP | Amphitrite ornata | |
| 1.11.1.7 | additional information | no substrate inhibition by 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid); no substrate inhibition by 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) | Amphitrite ornata | |
| 1.11.1.7 | additional information | enzyme does not exhibit any measurable substrate inhibition | Armoracia rusticana |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.11.1.7 | 0.012 | - |
H2O2 | 2,4,6-trichlorophenol, pH 7.0, temperature not specified in the publication | Armoracia rusticana | |
| 1.11.1.7 | 0.025 | - |
H2O2 | 2,4,6-trichlorophenol, pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 0.029 | - |
H2O2 | 2,4,6-trichlorophenol, pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 0.05 | - |
H2O2 | cosubstrate 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid), pH 7.0, temperature not specified in the publication | Armoracia rusticana | |
| 1.11.1.7 | 0.093 | - |
H2O2 | cosubstrate 2,4,6-tribromophenol, pH 7.0, temperature not specified in the publication | Armoracia rusticana | |
| 1.11.1.7 | 0.141 | - |
H2O2 | cosubstrate 2,4,6-tribromophenol, pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 0.165 | - |
H2O2 | cosubstrate 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid), pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 0.212 | - |
H2O2 | cosubstrate 2,4,6-tribromophenol, pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 0.229 | - |
2,4,6-Trichlorophenol | pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 0.312 | - |
2,4,6-tribromophenol | pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 0.335 | - |
H2O2 | cosubstrate 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid), pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 0.448 | - |
2,4,6-Trichlorophenol | pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 0.685 | - |
2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) | pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 1.02 | - |
2,4,6-tribromophenol | pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 2.07 | - |
2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) | pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 4.53 | - |
2,4,6-tribromophenol | pH 7.0, temperature not specified in the publication | Armoracia rusticana | |
| 1.11.1.7 | 5.1 | - |
2,4,6-Trichlorophenol | pH 7.0, temperature not specified in the publication | Armoracia rusticana | |
| 1.11.1.7 | 5.4 | - |
2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) | pH 7.0, temperature not specified in the publication | Armoracia rusticana | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.11.1.7 | Amphitrite ornata | - |
- |
- |
| 1.11.1.7 | Amphitrite ornata | Q9NAV8 | isoform DHP A | - |
| 1.11.1.7 | Armoracia rusticana | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.11.1.7 | commercial preparation | isoform C | Armoracia rusticana | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.11.1.7 | 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) + H2O2 | - |
Armoracia rusticana | ? + H2O | - |
? | |
| 1.11.1.7 | 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) + H2O2 | - |
Amphitrite ornata | ? + H2O | - |
? | |
| 1.11.1.7 | 2,4,6-tribromophenol + H2O2 | - |
Armoracia rusticana | ? + H2O | - |
? | |
| 1.11.1.7 | 2,4,6-tribromophenol + H2O2 | - |
Amphitrite ornata | ? + H2O | - |
? | |
| 1.11.1.7 | 2,4,6-trichlorophenol + H2O2 | - |
Armoracia rusticana | ? + H2O | - |
? | |
| 1.11.1.7 | 2,4,6-trichlorophenol + H2O2 | - |
Amphitrite ornata | ? + H2O | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.11.1.7 | dehaloperoxidase A | - |
Amphitrite ornata |
| 1.11.1.7 | dehaloperoxidase B | - |
Amphitrite ornata |
| 1.11.1.7 | DHP A | - |
Amphitrite ornata |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.11.1.7 | 0.7 | - |
2,4,6-Trichlorophenol | pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 1.05 | - |
2,4,6-Trichlorophenol | pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 1.83 | - |
2,4,6-tribromophenol | pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 1.87 | - |
2,4,6-tribromophenol | pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 13.67 | - |
2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) | pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 25.72 | - |
2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) | pH 7.0, temperature not specified in the publication | Amphitrite ornata | |
| 1.11.1.7 | 52.5 | - |
2,4,6-Trichlorophenol | pH 7.0, temperature not specified in the publication | Armoracia rusticana | |
| 1.11.1.7 | 223 | - |
2,4,6-tribromophenol | pH 7.0, temperature not specified in the publication | Armoracia rusticana | |
| 1.11.1.7 | 571 | - |
2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) | pH 7.0, temperature not specified in the publication | Armoracia rusticana | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
