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Literature summary extracted from

  • Bauer, S.; Schott, A.K.; Illarionova, V.; Bacher, A.; Huber, R.; Fischer, M.
    Biosynthesis of tetrahydrofolate in plants crystal structure of 7,8-dihydroneopterin aldolase from Arabidopsis thaliana reveals a novel adolase class (2004), J. Mol. Biol., 339, 967-979 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.2.60 expressed in Escherichia coli M15 [pREP4] cells Arabidopsis thaliana

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
4.1.2.60 sitting drop vapor diffusion method, using 0.1 M Tris hydrochloride (pH 7.2), 21% (w/v) polyethylene glycol 2000 MME, and 115 mM cyclohexylbutanoyl-N-hydroxyethylglucamide Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.2.60 7,8-dihydroneopterin 3'-triphosphate Arabidopsis thaliana
-
 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde triphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.2.60 Arabidopsis thaliana Q9SF23
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.2.60 Q-Sepharose column chromatography and Superdex 200 gel filtration Arabidopsis thaliana

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.2.60 7,8-dihydroneopterin 3'-triphosphate
-
 Arabidopsis thaliana 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde triphosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.2.60 homooctamer
-
 Arabidopsis thaliana

Synonyms

EC Number Synonyms Comment Organism
4.1.2.60 DHNA
-
 Arabidopsis thaliana
4.1.2.60 dihydroneopterin aldolase
-
 Arabidopsis thaliana