Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • El Gendy, A.; Rabie, I.; El Deeb, S.; El Amir, A.
    Importance of Schistosoma mansoni thioredoxin glutathione reductase 1- evaluation of its role in schistosomiasis diagnosis in human (2013), J. Med. Sci., 13, 635-646 .
No PubMed abstract available

Application

EC Number Application Comment Organism
1.8.1.B1 medicine enzyme can be used as a diagnostic target antigen for Schistosama mansoni infection in serum and urine. Sandwich ELISA detects the protein with high diagnostic efficiency in individuals with high or low worm burden Schistosoma mansoni

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.8.1.B1 0.00434
-
 5,5'-dithiobis(2-nitrobenzoic acid) pH not specified in the publication, temperature not specified in the publication Schistosoma mansoni
1.8.1.B1 0.0612
-
 glutathione disulfide pH not specified in the publication, temperature not specified in the publication Schistosoma mansoni

Organism

EC Number Organism UniProt Comment Textmining
1.8.1.B1 Schistosoma mansoni
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.1.B1 5,5'-dithiobis(2-nitrobenzoic acid) + NADPH + H+
-
 Schistosoma mansoni 2-nitro-5-thiobenzoate + NADP+
-
 ?
1.8.1.B1 glutathione disulfide + NADPH + H+
-
 Schistosoma mansoni 2 glutathione + NADP+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.1.B1 NADPH
-
 Schistosoma mansoni