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Literature summary extracted from

  • Bernardini, G.; Laschi, M.; Geminiani, M.; Braconi, D.; Vannuccini, E.; Lupetti, P.; Manetti, F.; Millucci, L.; Santucci, A.
    Homogentisate 1,2 dioxygenase is expressed in brain implications in alkaptonuria (2015), J. Inherit. Metab. Dis., 38, 807-814 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.13.11.5 homogentisate + O2 Mus musculus
-
 4-maleylacetoacetate
-
 ?
1.13.11.5 homogentisate + O2 Homo sapiens
-
 4-maleylacetoacetate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.5 Homo sapiens
-
-
-
1.13.11.5 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.5 brain cortex
-
 Mus musculus
-
1.13.11.5 brain cortex
-
 Homo sapiens
-
1.13.11.5 cerebellum
-
 Mus musculus
-
1.13.11.5 cerebellum
-
 Homo sapiens
-
1.13.11.5 corpus striatum
-
 Homo sapiens
-
1.13.11.5 forebrain
-
 Mus musculus
-
1.13.11.5 forebrain
-
 Homo sapiens
-
1.13.11.5 hippocampus
-
 Mus musculus
-
1.13.11.5 hippocampus
-
 Homo sapiens
-
1.13.11.5 IMR-32 cell
-
 Homo sapiens
-
1.13.11.5 neuronal cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.5 homogentisate + O2
-
 Mus musculus 4-maleylacetoacetate
-
 ?
1.13.11.5 homogentisate + O2
-
 Homo sapiens 4-maleylacetoacetate
-
 ?

Subunits

EC Number Subunits Comment Organism
1.13.11.5 ? x * 50000, SDS-PAGE Mus musculus
1.13.11.5 ? x * 50000, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
1.13.11.5 HgD
-
 Mus musculus
1.13.11.5 HgD
-
 Homo sapiens