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Literature summary extracted from
- AS2077715 is a selective inhibitor of fungal mitochondrial cytochrome bc1 complex (2014), J. Antibiot., 67, 713-716 .
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.1.1.8 | AS2077715 | selective inhibitor, IC50 of 0.9 ng/ml | Trichophyton mentagrophytes |  |
| 7.1.1.8 | funiculosin | - |
Trichophyton mentagrophytes | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 7.1.1.8 | mitochondrion | - |
Trichophyton mentagrophytes | 5739 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.1.1.8 | ubiquinol + ferricytochrome c | Trichophyton mentagrophytes | - |
ubiquinone + ferrocytochrome c + H+ | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.1.1.8 | Trichophyton mentagrophytes | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.1.1.8 | ubiquinol + ferricytochrome c | - |
Trichophyton mentagrophytes | ubiquinone + ferrocytochrome c + H+ | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 7.1.1.8 | cytochrome bc1 complex | - |
Trichophyton mentagrophytes |
| 7.1.1.8 | ubiquinol-cytochrome c reductase complex III | - |
Trichophyton mentagrophytes |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.1.1.8 | cytochrome c | - |
Trichophyton mentagrophytes | |
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