EC Number | Crystallization (Comment) | Organism |
---|---|---|
1.13.11.27 | crystal structure analysis of HPPD-Fe(II)-acetate complex, PDB ID 1CJX | Pseudomonas fluorescens |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.13.11.27 | Fe | Fe(II), Fe(III), and Fe(IV) during oxygenation and hydroxylation, overview. The iron ion is coordinated by a His-His-Glu triad, structure of HPPD-Fe(II)-acetate complex, overview | Pseudomonas fluorescens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.13.11.27 | 4-hydroxyphenylpyruvate + O2 | Pseudomonas fluorescens | - |
homogentisate + CO2 | - |
? | |
1.13.11.27 | 4-hydroxyphenylpyruvate + O2 | Pseudomonas fluorescens ATCC 13525 | - |
homogentisate + CO2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.13.11.27 | Pseudomonas fluorescens | - |
- |
- |
1.13.11.27 | Pseudomonas fluorescens ATCC 13525 | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
1.13.11.27 | 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2 | reaction mechanism, quantum mechanics/molecular mechanics calculations and simulations, detailed overview | Pseudomonas fluorescens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.13.11.27 | 4-hydroxyphenylpyruvate + O2 | - |
Pseudomonas fluorescens | homogentisate + CO2 | - |
? | |
1.13.11.27 | 4-hydroxyphenylpyruvate + O2 | - |
Pseudomonas fluorescens ATCC 13525 | homogentisate + CO2 | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.13.11.27 | More | enzyme structure comparisons, structure homology modeling, overview | Pseudomonas fluorescens |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.13.11.27 | HPPD | - |
Pseudomonas fluorescens |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.13.11.27 | metabolism | suggested hydroxylation mechanisms for HMS and HPPD and pathways leading to alternative products: oxepinone and quinolacetate | Pseudomonas fluorescens |
1.13.11.27 | additional information | molecular dynamics simulations are performed for the HPPD-Fe(IV)=O-hydroxyphenylacetate complex in order to obtain a reliable starting structure for quantum mechanics/molecular mechanics calculations of ring hydroxylation and coupled rearrangement reactions catalyzed by the enzyme HPPD, structure of HPPD-Fe(II)-acetate complex, structure homology modeling, overview | Pseudomonas fluorescens |