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Literature summary extracted from

  • Li, R.; Xin, S.; Tao, C.; Jin, X.; Li, H.
    Cotton ascorbate oxidase promotes cell growth in cultured tobacco bright Yellow-2 cells through generation of apoplast oxidation (2017), Int. J. Mol. Sci., 18, 1346.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.10.3.3 expressed in Nicotiana tabacum BY-2 cells Gossypium hirsutum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.10.3.3 cell wall
-
 Gossypium hirsutum 5618
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.10.3.3 Co2+ contains copper Gossypium hirsutum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.10.3.3 L-ascorbate + O2 Gossypium hirsutum
-
 monodehydroascorbate + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.10.3.3 Gossypium hirsutum A0A1S5QMW4
-
-
1.14.18.6 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.10.3.3 cotton fibre
-
 Gossypium hirsutum
-
1.10.3.3 leaf
-
 Gossypium hirsutum
-
1.10.3.3 root
-
 Gossypium hirsutum
-
1.10.3.3 stem
-
 Gossypium hirsutum
-
1.14.18.6 Neuro2A cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.10.3.3 L-ascorbate + O2
-
 Gossypium hirsutum monodehydroascorbate + H2O
-
 ?

Subunits

EC Number Subunits Comment Organism
1.10.3.3 ? x * 62800, calculated from amino acid sequence Gossypium hirsutum

Synonyms

EC Number Synonyms Comment Organism
1.10.3.3 AO1
-
 Gossypium hirsutum
1.14.18.6 FA2H
-
 Mus musculus
1.14.18.6 fatty acid 2-hydroxylase
-
 Mus musculus

Expression

EC Number Organism Comment Expression
1.10.3.3 Gossypium hirsutum expression is upregulated under indole-3-acetic acid treatment. The ascorbate oxidase gene AO1 is preferentially expressed during the fiber cell fast elongation period at the mRNA level up
1.14.18.6 Mus musculus nimodipine promotes expression of fatty acid 2-hydroxylase in a surgical stress model based on Neuro2a cells up

General Information

EC Number General Information Comment Organism
1.10.3.3 physiological function the enzyme plays an important role in fiber cell elongation and may promote cell growth by generating the oxidation of apoplasts, via the auxin-mediated signaling pathway Gossypium hirsutum