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Literature summary extracted from

  • Solyanikova, I.P.; Borzova, O.V.; Emelyanova, E.V.
    Kinetics of interaction between substrates/substrate analogs and benzoate 1,2-dioxygenase from benzoate-degrading Rhodococcus opacus 1CP (2017), Folia Microbiol. (Praha), 62, 355-362 .
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.12.10 2-Chlorobenzoate
-
Rhodococcus opacus
1.14.12.10 3,5-dichlorobenzoate
-
Rhodococcus opacus
1.14.12.10 3-methylbenzoate
-
Rhodococcus opacus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.12.10 benzoate + NADH + H+ + O2 Rhodococcus opacus
-
(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+
-
?
1.14.12.10 benzoate + NADH + H+ + O2 Rhodococcus opacus 1CP
-
(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.14.12.10 Rhodococcus opacus
-
-
-
1.14.12.10 Rhodococcus opacus 1CP
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.12.10 benzoate + NADH + H+ + O2
-
Rhodococcus opacus (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+
-
?
1.14.12.10 benzoate + NADH + H+ + O2
-
Rhodococcus opacus 1CP (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+
-
?

Synonyms

EC Number Synonyms Comment Organism
1.14.12.10 BDO
-
Rhodococcus opacus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.12.10 NADH
-
Rhodococcus opacus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.14.12.10 0.0147
-
3,5-dichlorobenzoate at pH 8.0 and 25°C Rhodococcus opacus
1.14.12.10 0.3375
-
2-Chlorobenzoate at pH 8.0 and 25°C Rhodococcus opacus
1.14.12.10 0.8703
-
3-methylbenzoate at pH 8.0 and 25°C Rhodococcus opacus