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Literature summary extracted from
- Re-evaluation of the function of the F420 dehydrogenase in electron transport of Methanosarcina mazei (2011), FEBS J., 278, 1277-1287 .
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.5.98.3 | membrane | - |
Methanosarcina mazei | 16020 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.5.98.3 | reduced coenzyme F420 + methanophenazine | Methanosarcina mazei | - |
oxidized coenzyme F420 + dihydromethanophenazine | - |
? |  |
| 1.5.98.3 | reduced coenzyme F420 + methanophenazine | Methanosarcina mazei DSM 7222 | - |
oxidized coenzyme F420 + dihydromethanophenazine | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.5.98.3 | Methanosarcina mazei | - |
- |
- |
| 1.5.98.3 | Methanosarcina mazei DSM 7222 | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.5.98.3 | oxidized coenzyme F420 + reduced ferredoxin | - |
Methanosarcina mazei | reduced coenzyme F420 + oxidized ferredoxin | - |
? | |
| 1.5.98.3 | oxidized coenzyme F420 + reduced ferredoxin | - |
Methanosarcina mazei DSM 7222 | reduced coenzyme F420 + oxidized ferredoxin | - |
? | |
| 1.5.98.3 | reduced coenzyme F420 + methanophenazine | - |
Methanosarcina mazei | oxidized coenzyme F420 + dihydromethanophenazine | - |
? | |
| 1.5.98.3 | reduced coenzyme F420 + methanophenazine | - |
Methanosarcina mazei DSM 7222 | oxidized coenzyme F420 + dihydromethanophenazine | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.5.98.3 | F420H2 dehydrogenase | - |
Methanosarcina mazei |
| 1.5.98.3 | Fpo | - |
Methanosarcina mazei |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 1.5.98.3 | malfunction | knockout mutants of the membrane-bound F420 dehydrogenase exhibit severe growth deficiencies with trimethylamine, but not with acetate, as substrates | Methanosarcina mazei |
| 1.5.98.3 | metabolism | the enzyme plays a major role in the oxidative part of methylotrophic methanogenesis | Methanosarcina mazei |
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Release 2023.1 (January 2023)
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