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Literature summary extracted from

  • Tehrani, M.B.; Emami, S.; Asadi, M.; Saeedi, M.; Mirzahekmati, M.; Ebrahimi, S.M.; Mahdavi, M.; Nadri, H.; Moradi, A.; Moghadam, F.H.; Farzipour, S.; Vosooghi, M.; Foroumadi, A.; Shafiee, A.
    Imidazo[2,1-b]thiazole derivatives as new inhibitors of 15-lipoxygenase (2014), Eur. J. Med. Chem., 87, 759-764 .
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.11.33 3-(4-bromophenyl)-6-(4-chlorophenyl)-N-(2,4,4-trimethylpentan-2-yl)imidazo[2,1-b][1,3]thiazol-5-amine
-
 Homo sapiens
1.13.11.33 3-(4-bromophenyl)-6-(4-chlorophenyl)-N-cyclohexylimidazo[2,1-b][1,3]thiazol-5-amine
-
 Homo sapiens
1.13.11.33 3-(4-bromophenyl)-N-cyclohexyl-6-(2-nitrophenyl)imidazo[2,1-b][1,3]thiazol-5-amine
-
 Homo sapiens
1.13.11.33 3-(4-methoxyphenyl)-6-phenyl-N-(2,4,4-trimethylpentan-2-yl)imidazo[2,1-b][1,3]thiazol-5-amine protective activity of compound 5i against H2O2-induced cell death in differentiated PC12 cells Homo sapiens
1.13.11.33 6-(2-bromophenyl)-N-cyclohexyl-3-phenylimidazo[2,1-b][1,3]thiazol-5-amine
-
 Homo sapiens
1.13.11.33 6-(2-nitrophenyl)-3-phenyl-N-(2,4,4-trimethylpentan-2-yl)imidazo[2,1-b][1,3]thiazol-5-amine
-
 Homo sapiens
1.13.11.33 6-(4-nitrophenyl)-3-phenyl-N-(2,4,4-trimethylpentan-2-yl)imidazo[2,1-b][1,3]thiazol-5-amine
-
 Homo sapiens
1.13.11.33 additional information imidazo[2,1-b]thiazole derivatives as inhibitors of 15-lipoxygenase, synthesis and evaluation of series of 3,6-diphenylimidazo[2,1-b]thiazol-5-amine derivatives, docking study, overview Homo sapiens
1.13.11.33 N-(tert-butyl)-3-phenyl-6-(p-tolyl)imidazo[2,1-b]thiazol-5-amine
-
 Homo sapiens
1.13.11.33 N-(tert-butyl)-6-(4-chlorophenyl)-3-phenylimidazo[2,1-b]thiazol-5-amine
-
 Homo sapiens
1.13.11.33 N-(tert-butyl)-6-(4-methoxyphenyl)-3-phenylimidazo[2,1-b]thiazol-5-amine
-
 Homo sapiens
1.13.11.33 N-(tert-butyl)-6-(4-nitrophenyl)-3-phenylimidazo[2,1-b]thiazol-5-amine
-
 Homo sapiens
1.13.11.33 N-cyclohexyl-6-(2-fluorophenyl)-3-phenylimidazo[2,1-b][1,3]thiazol-5-amine
-
 Homo sapiens
1.13.11.33 N-cyclohexyl-6-(4-methoxyphenyl)-3-phenylimidazo[2,1-b][1,3]thiazol-5-amine
-
 Homo sapiens
1.13.11.33 N-cyclohexyl-6-(4-nitrophenyl)-3-phenylimidazo[2,1-b][1,3]thiazol-5-amine
-
 Homo sapiens
1.13.11.33 quercetin
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.33 Homo sapiens P16050
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