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Literature summary extracted from

  • Shi, F.; Fang, H.; Niu, T.; Lu, Z.
    Overexpression of ppc and lysC to improve the production of 4-hydroxyisoleucine and its precursor L-isoleucine in recombinant Corynebacterium glutamicum ssp. lactofermentum (2016), Enzyme Microb. Technol., 87-88, 79-85 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.11.45 expressed in Corynebacterium glutamicum ssp. lactofermentum strain SN01 Bacillus thuringiensis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.11.45 L-isoleucine + 2-oxoglutarate + O2 Bacillus thuringiensis
-
 (4S)-4-hydroxy-L-isoleucine + succinate + CO2
-
 ?
1.14.11.45 L-isoleucine + 2-oxoglutarate + O2 Bacillus thuringiensis YBT-1520
-
 (4S)-4-hydroxy-L-isoleucine + succinate + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.11.45 Bacillus thuringiensis
-
-
-
1.14.11.45 Bacillus thuringiensis YBT-1520
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.11.45 L-isoleucine + 2-oxoglutarate + O2
-
 Bacillus thuringiensis (4S)-4-hydroxy-L-isoleucine + succinate + CO2
-
 ?
1.14.11.45 L-isoleucine + 2-oxoglutarate + O2
-
 Bacillus thuringiensis YBT-1520 (4S)-4-hydroxy-L-isoleucine + succinate + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.11.45 IDO
-
 Bacillus thuringiensis
1.14.11.45 L-isoleucine dioxygenase
-
 Bacillus thuringiensis