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Literature summary extracted from

  • Tao, R.; Jiang, Y.; Zhu, F.; Yang, S.
    A one-pot system for production of L-2-aminobutyric acid from L-threonine by L-threonine deaminase and a NADH-regeneration system based on L-leucine dehydrogenase and formate dehydrogenase (2014), Biotechnol. Lett., 36, 835-841 .
    View publication on PubMed

Application

EC Number Application Comment Organism
1.4.1.9 synthesis production of L-2-aminobutanoate from L-threonine via overexpression of L-threonine deaminase from Escherichia coli, L-leucine dehydrogenase from Bacillus cereus, and formate dehydrogenase from Pseudomonas sp. in Escherichia coli with formate as a cosubstrate for NADH regeneration. 30 mol L-threonine are converted to 29.2 mol L-2-aminobutanoate with 97.3 % theoretical yield and with a productivity of 6.37 g/l/h at 50 l Bacillus cereus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.4.1.9 expression in Escherichia coli Bacillus cereus

Organism

EC Number Organism UniProt Comment Textmining
1.4.1.9 Bacillus cereus P0A392
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1.4.1.9 Bacillus cereus DSM 31 P0A392
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