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Literature summary extracted from

  • Adeboye, P.T.; Olsson, L.; Bettiga, M.
    A coniferyl aldehyde dehydrogenase gene from Pseudomonas sp. strain HR199 enhances the conversion of coniferyl aldehyde by Saccharomyces cerevisiae (2016), Biores. Technol., 212, 11-19 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.1.68 recombinant expression of the enzyme in Saccharomyces cerevisiae strain CEN.PK102-3A, deficient for acetaldehyde dehydrogenase Ald5 via deletion of ALD5, CALDH enzyme expression leads to increased coniferyl aldehyde conversion in the recombinant yeast strain. Effect of the conversion of coniferyl aldehyde on the lag phase of recombinant strains, overview Pseudomonas sp. HR199

Protein Variants

EC Number Protein Variants Comment Organism
1.2.1.68 additional information improved endogenous conversion of phenolic compounds by heterologous expression of coniferyl aldehyde dehydrogenase enzyme from Pseudomonas in Saccharomyces cerevisiae, overview Pseudomonas sp. HR199

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.68 coniferaldehyde + CoA + NADP+ Pseudomonas sp. HR199
-
feruloyl-CoA + NADPH + H+
-
?
1.2.1.68 coniferaldehyde + CoA + NADP+ Pseudomonas sp. HR199 DSM 7063
-
feruloyl-CoA + NADPH + H+
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.68 Pseudomonas sp. HR199 Q86447
-
-
1.2.1.68 Pseudomonas sp. HR199 DSM 7063 Q86447
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.68 additional information the maximum specific growth rates of the strains in decreased by coniferaldehyde, no growth at 1.4 M coniferaldehyde Pseudomonas sp. HR199
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.68 coniferaldehyde + CoA + NADP+
-
Pseudomonas sp. HR199 feruloyl-CoA + NADPH + H+
-
?
1.2.1.68 coniferaldehyde + CoA + NADP+
-
Pseudomonas sp. HR199 DSM 7063 feruloyl-CoA + NADPH + H+
-
?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.68 CALDH
-
Pseudomonas sp. HR199

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.68 NADP+
-
Pseudomonas sp. HR199