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Literature summary extracted from

  • Fujisawa, Y.; Napoli, E.; Wong, S.; Song, G.; Yamaguchi, R.; Matsui, T.; Nagasaki, K.; Ogata, T.; Giulivi, C.
    Impact of a novel homozygous mutation in nicotinamide nucleotide transhydrogenase on mitochondrial DNA integrity in a case of familial glucocorticoid deficiency (2015), BBA Clin., 3, 70-78 .
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
1.6.1.2 F215S the mutant shows 31% of wild type activity Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.6.1.2 mitochondrion
-
Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.6.1.2 NADPH + NAD+ Homo sapiens
-
NADP+ + NADH
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.6.1.2 Homo sapiens Q13423
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.6.1.2 blood
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.6.1.2 NADPH + 3-acetylpyridine adenine dinucleotide
-
Homo sapiens NADP+ + reduced 3-acetylpyridine adenine dinucleotide
-
?
1.6.1.2 NADPH + NAD+
-
Homo sapiens NADP+ + NADH
-
?

Synonyms

EC Number Synonyms Comment Organism
1.6.1.2 nicotinamide nucleotide transhydrogenase
-
Homo sapiens
1.6.1.2 NNT
-
Homo sapiens