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Literature summary extracted from

  • Zhang, W.; Niu, Z.; Liao, C.; Chen, L.
    Isolation and characterization of Pseudomonas sp. strain capable of degrading diethylstilbestrol (2013), Appl. Microbiol. Biotechnol., 97, 4095-4104 .
    View publication on PubMed

Application

EC Number Application Comment Organism
1.1.2.8 environmental protection potential application of Pseudomonas sp. strain J51 in the treatment of DES-contaminated freshwater and seawater environments Pseudomonas sp.

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.2.8 sequence comparisons and phylogenetic tree, real-time reverse transcriptase PCR expression analysis Pseudomonas sp.
1.1.2.8 sequence comparisons and phylogenetic tree, real-time reverse transcriptase PCR expression analysis Pseudomonas stutzeri
1.1.2.8 sequence comparisons and phylogenetic tree, real-time reverse transcriptase PCR expression analysis Pseudomonas mendocina

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.2.8 diethylstilbestrol + pyrroloquinoline quinone Pseudomonas sp. i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol
-
 ?
1.1.2.8 diethylstilbestrol + pyrroloquinoline quinone Pseudomonas stutzeri i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol
-
 ?
1.1.2.8 diethylstilbestrol + pyrroloquinoline quinone Pseudomonas mendocina i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol
-
 ?
1.1.2.8 diethylstilbestrol + pyrroloquinoline quinone Pseudomonas sp. J51 i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol
-
 ?
1.1.2.8 diethylstilbestrol + pyrroloquinoline quinone Pseudomonas stutzeri ATCC 14405 i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol
-
 ?
1.1.2.8 diethylstilbestrol + pyrroloquinoline quinone Pseudomonas mendocina YMP i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.2.8 Pseudomonas mendocina
-
-
-
1.1.2.8 Pseudomonas mendocina YMP
-
-
-
1.1.2.8 Pseudomonas sp.
-
-
-
1.1.2.8 Pseudomonas sp. J51
-
-
-
1.1.2.8 Pseudomonas stutzeri
-
-
-
1.1.2.8 Pseudomonas stutzeri ATCC 14405
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.2.8 diethylstilbestrol + pyrroloquinoline quinone i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol Pseudomonas sp. diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol
-
 ?
1.1.2.8 diethylstilbestrol + pyrroloquinoline quinone i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol Pseudomonas stutzeri diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol
-
 ?
1.1.2.8 diethylstilbestrol + pyrroloquinoline quinone i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol Pseudomonas mendocina diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol
-
 ?
1.1.2.8 diethylstilbestrol + pyrroloquinoline quinone i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol Pseudomonas sp. J51 diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol
-
 ?
1.1.2.8 diethylstilbestrol + pyrroloquinoline quinone i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol Pseudomonas stutzeri ATCC 14405 diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol
-
 ?
1.1.2.8 diethylstilbestrol + pyrroloquinoline quinone i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol Pseudomonas mendocina YMP diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol
-
 ?

Subunits

EC Number Subunits Comment Organism
1.1.2.8 ? x * 67951, sequence calculation Pseudomonas stutzeri
1.1.2.8 ? x * 68334, sequence calculation Pseudomonas mendocina

Synonyms

EC Number Synonyms Comment Organism
1.1.2.8 PQQ-dependent type I alcohol dehydrogenase
-
 Pseudomonas stutzeri
1.1.2.8 PQQ-dependent type I alcohol dehydrogenase
-
 Pseudomonas mendocina
1.1.2.8 quinoprotein alcohol dehydrogenase
-
 Pseudomonas sp.

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.2.8 pyrroloquinoline quinone
-
 Pseudomonas sp.
1.1.2.8 pyrroloquinoline quinone
-
 Pseudomonas stutzeri
1.1.2.8 pyrroloquinoline quinone
-
 Pseudomonas mendocina

pI Value

EC Number Organism Comment pI Value Maximum pI Value
1.1.2.8 Pseudomonas mendocina sequence calculation
-
 6.77
1.1.2.8 Pseudomonas stutzeri sequence calculation
-
 6.96

Expression

EC Number Organism Comment Expression
1.1.2.8 Pseudomonas sp. the enzyme is induced by diethylstilbestrol, presence of diethylstilbestrol causes a 5.2fold increase in the mRNA level of the gene encoding quinoprotein alcohol dehydrogenase up

General Information

EC Number General Information Comment Organism
1.1.2.8 evolution quinoprotein alcohol dehydrogenase usually occupies PQQ as a cofactor and belongs to the family of PQQ-dependent type I alcohol dehydrogenases, sequence comparisons and phylogenetic tree Pseudomonas sp.
1.1.2.8 evolution quinoprotein alcohol dehydrogenase usually occupies PQQ as a cofactor and belongs to the family of PQQ-dependent type I alcohol dehydrogenases, sequence comparisons and phylogenetic tree Pseudomonas stutzeri
1.1.2.8 evolution quinoprotein alcohol dehydrogenase usually occupies PQQ as a cofactor and belongs to the family of PQQ-dependent type I alcohol dehydrogenases, sequence comparisons and phylogenetic tree Pseudomonas mendocina
1.1.2.8 physiological function the enzyme is involved in diethylstilbestrol degradation Pseudomonas sp.
1.1.2.8 physiological function the enzyme is involved in diethylstilbestrol degradation Pseudomonas stutzeri
1.1.2.8 physiological function the enzyme is involved in diethylstilbestrol degradation Pseudomonas mendocina