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Literature summary extracted from
- Isolation and characterization of Pseudomonas sp. strain capable of degrading diethylstilbestrol (2013), Appl. Microbiol. Biotechnol., 97, 4095-4104.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 1.1.2.8 | environmental protection | potential application of Pseudomonas sp. strain J51 in the treatment of DES-contaminated freshwater and seawater environments | Pseudomonas sp. |
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.1.2.8 | sequence comparisons and phylogenetic tree, real-time reverse transcriptase PCR expression analysis | Ectopseudomonas mendocina |
| 1.1.2.8 | sequence comparisons and phylogenetic tree, real-time reverse transcriptase PCR expression analysis | Pseudomonas sp. |
| 1.1.2.8 | sequence comparisons and phylogenetic tree, real-time reverse transcriptase PCR expression analysis | Stutzerimonas stutzeri |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.2.8 | diethylstilbestrol + pyrroloquinoline quinone | Stutzerimonas stutzeri | i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol | diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol | - |
? |  |
| 1.1.2.8 | diethylstilbestrol + pyrroloquinoline quinone | Ectopseudomonas mendocina | i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol | diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol | - |
? | |
| 1.1.2.8 | diethylstilbestrol + pyrroloquinoline quinone | Pseudomonas sp. | i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol | diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol | - |
? | |
| 1.1.2.8 | diethylstilbestrol + pyrroloquinoline quinone | Stutzerimonas stutzeri ATCC 14405 | i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol | diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol | - |
? | |
| 1.1.2.8 | diethylstilbestrol + pyrroloquinoline quinone | Ectopseudomonas mendocina YMP | i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol | diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol | - |
? | |
| 1.1.2.8 | diethylstilbestrol + pyrroloquinoline quinone | Pseudomonas sp. J51 | i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol | diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.2.8 | Ectopseudomonas mendocina | - |
- |
- |
| 1.1.2.8 | Ectopseudomonas mendocina YMP | - |
- |
- |
| 1.1.2.8 | Pseudomonas sp. | - |
- |
- |
| 1.1.2.8 | Pseudomonas sp. J51 | - |
- |
- |
| 1.1.2.8 | Stutzerimonas stutzeri | - |
- |
- |
| 1.1.2.8 | Stutzerimonas stutzeri ATCC 14405 | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.2.8 | diethylstilbestrol + pyrroloquinoline quinone | i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol | Stutzerimonas stutzeri | diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol | - |
? | |
| 1.1.2.8 | diethylstilbestrol + pyrroloquinoline quinone | i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol | Ectopseudomonas mendocina | diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol | - |
? | |
| 1.1.2.8 | diethylstilbestrol + pyrroloquinoline quinone | i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol | Pseudomonas sp. | diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol | - |
? | |
| 1.1.2.8 | diethylstilbestrol + pyrroloquinoline quinone | i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol | Stutzerimonas stutzeri ATCC 14405 | diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol | - |
? | |
| 1.1.2.8 | diethylstilbestrol + pyrroloquinoline quinone | i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol | Ectopseudomonas mendocina YMP | diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol | - |
? | |
| 1.1.2.8 | diethylstilbestrol + pyrroloquinoline quinone | i.e. 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol | Pseudomonas sp. J51 | diethylstilbestrol 4-semiquinone + pyrroloquinoline quinol | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.1.2.8 | ? | x * 67951, sequence calculation | Stutzerimonas stutzeri |
| 1.1.2.8 | ? | x * 68334, sequence calculation | Ectopseudomonas mendocina |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.1.2.8 | PQQ-dependent type I alcohol dehydrogenase | - |
Stutzerimonas stutzeri |
| 1.1.2.8 | PQQ-dependent type I alcohol dehydrogenase | - |
Ectopseudomonas mendocina |
| 1.1.2.8 | quinoprotein alcohol dehydrogenase | - |
Pseudomonas sp. |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.2.8 | pyrroloquinoline quinone | - |
Stutzerimonas stutzeri | |
| 1.1.2.8 | pyrroloquinoline quinone | - |
Ectopseudomonas mendocina | |
| 1.1.2.8 | pyrroloquinoline quinone | - |
Pseudomonas sp. | |
pI Value
| EC Number | Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|---|
| 1.1.2.8 | Ectopseudomonas mendocina | sequence calculation | - |
6.77 |
| 1.1.2.8 | Stutzerimonas stutzeri | sequence calculation | - |
6.96 |
Expression
| EC Number | Organism | Comment | Expression |
|---|---|---|---|
| 1.1.2.8 | Pseudomonas sp. | the enzyme is induced by diethylstilbestrol, presence of diethylstilbestrol causes a 5.2fold increase in the mRNA level of the gene encoding quinoprotein alcohol dehydrogenase | up |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 1.1.2.8 | evolution | quinoprotein alcohol dehydrogenase usually occupies PQQ as a cofactor and belongs to the family of PQQ-dependent type I alcohol dehydrogenases, sequence comparisons and phylogenetic tree | Stutzerimonas stutzeri |
| 1.1.2.8 | evolution | quinoprotein alcohol dehydrogenase usually occupies PQQ as a cofactor and belongs to the family of PQQ-dependent type I alcohol dehydrogenases, sequence comparisons and phylogenetic tree | Ectopseudomonas mendocina |
| 1.1.2.8 | evolution | quinoprotein alcohol dehydrogenase usually occupies PQQ as a cofactor and belongs to the family of PQQ-dependent type I alcohol dehydrogenases, sequence comparisons and phylogenetic tree | Pseudomonas sp. |
| 1.1.2.8 | physiological function | the enzyme is involved in diethylstilbestrol degradation | Stutzerimonas stutzeri |
| 1.1.2.8 | physiological function | the enzyme is involved in diethylstilbestrol degradation | Ectopseudomonas mendocina |
| 1.1.2.8 | physiological function | the enzyme is involved in diethylstilbestrol degradation | Pseudomonas sp. |
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