EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.14.94 | (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2 | Homo sapiens | - |
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.14.94 | Homo sapiens | Q08477 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.14.94 | kidney | CYP4F3B | Homo sapiens | - |
1.14.14.94 | liver | CYP4F3B | Homo sapiens | - |
1.14.14.94 | neutrophil | CYP4F3A | Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.14.94 | (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2 | - |
Homo sapiens | (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.14.94 | CYP4 omega-hydroxylase | - |
Homo sapiens |
1.14.14.94 | CYP4F3 | CYP4F3 undergoes tissue-specific alternative splicing to CYP4F3A and CYP4F3B | Homo sapiens |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.14.14.94 | physiological function | CYP4F3B plays a central role in the inactivation and elimination of leukotrienes from systemic circulation during the resolution of inflammation | Homo sapiens |