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Literature summary extracted from
- Role of cysteine-58 and cysteine-95 residues in the thiol di-sulfide oxidoreductase activity of macrophage migration inhibitory factor-2 of Wuchereria bancrofti (2016), Acta Trop., 153, 14-20 .
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 1.8.4.2 | homology modeling.Csteine residues, Cys58 and Cys95 come in close proximity in the tertiary structure with pKa value 9. The residues are involved in the disulfide oxidoreductase catalytic activity | Wuchereria bancrofti |
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 1.8.4.2 | C58S | complete loss of oxidoreductase activtiy | Wuchereria bancrofti |
| 1.8.4.2 | C95S | complete loss of oxidoreductase activtiy | Wuchereria bancrofti |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.8.4.2 | Wuchereria bancrofti | A0A088FMA5 | - |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.4.2 | insulin disulfide + dithiothreitol | - |
Wuchereria bancrofti | insulin + dithiothreitol disulfide | - |
? |  |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.8.4.2 | ? | x * 17000, SDS-PAGE | Wuchereria bancrofti |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.8.4.2 | mcrophage migration inhibitory factor-2 | - |
Wuchereria bancrofti |
| 1.8.4.2 | Mif-2 | - |
Wuchereria bancrofti |
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Release 2023.1 (January 2023)
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