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Literature summary extracted from

  • Almanzar, G.; Mayerl, C.; Seitz, J.C.; Hoefner, K.; Brunner, A.; Wild, V.; Jahn, D.; Geier, A.; Fassnacht, M.; Prelog, M.
    Expression of 11beta-hydroxysteroid-dehydrogenase type 2 in human thymus (2016), Steroids, 110, 35-40.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.146 40000
-
 x * 40000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.146 cortisol + NADP+ Homo sapiens
-
 cortisone + NADPH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.146 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.146 kidney
-
 Homo sapiens
-
1.1.1.146 peripheral blood mononuclear cell
-
 Homo sapiens
-
1.1.1.146 thymus significant expression of isoform 11beta-HSD2 protein is found at single cell level in thymus parenchyma, at perivascular sites of capillaries and small vessels penetrating the thymus lobuli and within Hassall's bodies Homo sapiens
-
1.1.1.146 umbilical vein endothelial cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.146 cortisol + NADP+
-
 Homo sapiens cortisone + NADPH + H+
-
 ?

Subunits

EC Number Subunits Comment Organism
1.1.1.146 ? x * 40000, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
1.1.1.146 11beta-HSD2
-
 Homo sapiens
1.1.1.146 11beta-hydroxysteroid dehydrogenase type 2
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.146 NADP+
-
 Homo sapiens