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Literature summary extracted from

  • Lu, X.; Hao, L.; Wang, F.; Huang, C.
    Molecular cloning, characterization and expression analysis of a gene encoding hydroxyphenylpyruvate reductase involved in rosmarinic acid biosynthesis pathway from Perilla frutescens (2014), Proc. 2012 Int. Conf. Appl. Biotechnol., 251 LNEE, 1807-1820.
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.237 gene PfHPPR, DNA and amino acid sequence determination and analysis, sequence comparisons, quantitative real-time PCR enzyme expression analysis Perilla frutescens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.237 34422
-
-
 Perilla frutescens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.237 3-(4-hydroxyphenyl)pyruvate + NADH + H+ Perilla frutescens
-
 3-(4-hydroxyphenyl)lactate + NAD+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.237 Perilla frutescens F8RGR8
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.237 leaf
-
 Perilla frutescens
-
1.1.1.237 additional information quantitative real-time PCR analysis of the transcription pattern indicates that the PfHPPR expresses constitutively in all examined tissues but most highly in leaves Perilla frutescens
-
1.1.1.237 root
-
 Perilla frutescens
-
1.1.1.237 stem
-
 Perilla frutescens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.237 3-(4-hydroxyphenyl)pyruvate + NADH + H+
-
 Perilla frutescens 3-(4-hydroxyphenyl)lactate + NAD+
-
 r

Subunits

EC Number Subunits Comment Organism
1.1.1.237 ? x * 34422, sequence calculation Perilla frutescens
1.1.1.237 More secondary structure, and homology-based structural modeling Perilla frutescens

Synonyms

EC Number Synonyms Comment Organism
1.1.1.237 HPPR
-
 Perilla frutescens

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.237 NADH
-
 Perilla frutescens

pI Value

EC Number Organism Comment pI Value Maximum pI Value
1.1.1.237 Perilla frutescens sequence calculation
-
 5.58

Expression

EC Number Organism Comment Expression
1.1.1.237 Perilla frutescens expression of PfHPPR can be induced by several factors such as abscisic acid (ABA), salicylic acid (SA), and ultraviolet-B radiation (UV-B) up

General Information

EC Number General Information Comment Organism
1.1.1.237 evolution comparison of HPPR gene sequences from Perilla frutescens and other species reveals that the HPPR genes are structurally conserved and might possess similar functions Perilla frutescens
1.1.1.237 metabolism hydroxyphenylpyruvate reductase is involved in rosmarinic acid biosynthesis via the tyrosine pathway Perilla frutescens
1.1.1.237 additional information homology-based structural modeling Perilla frutescens