Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Singh, G.
    Mitochondrial FAD-linked glycerol-3-phosphate dehydrogenase: a target for cancer therapeutics (2014), Pharmaceuticals, 7, 192-206.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.5.3 2,2-dimethyl-5-nitro-2H-benzimidazole
-
 Homo sapiens
1.1.5.3 2-[(7-nitro-3-oxo-2,1,3l5-benzoxadiazol-4-yl)oxy]phenol
-
 Homo sapiens
1.1.5.3 2-[(E)-(4-hydroxyphenyl)diazenyl]-1-benzothiophene-3-ol
-
 Homo sapiens
1.1.5.3 5-[(E)-(3-chlorophenyl)diazenyl]-2-hydroxybenzaldehyde
-
 Homo sapiens
1.1.5.3 cisplatin
-
 Homo sapiens
1.1.5.3 ethyl 4-(3-oxo-1,2-thiazol-2(3H)-yl)benzoate
-
 Homo sapiens
1.1.5.3 N-(3,5-dibromo-4-hydroxyphenyl)-4-methylbenzene-1-sulfonamide
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.5.3 mitochondrion
-
 Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.5.3 sn-glycerol 3-phosphate + a quinone Homo sapiens
-
 glycerone phosphate + a quinol
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.5.3 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.5.3 PC-3 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.5.3 sn-glycerol 3-phosphate + a quinone
-
 Homo sapiens glycerone phosphate + a quinol
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.5.3 FAD-linked glycerol-3-phosphate dehydrogenase
-
 Homo sapiens
1.1.5.3 flavin-linked glycerol-3-phosphate ubiquinone oxidoreductase
-
 Homo sapiens
1.1.5.3 GPD2
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.5.3 FAD
-
 Homo sapiens