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Literature summary extracted from

  • Schwarz, M.; Lund, E.G.; Lathe, R.; Björkhem, I.; Russell, D.W.
    Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA (1997), J. Biol. Chem., 272, 23995-24001.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.29 cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 Mus musculus dietary cholesterol or colestipol do not affect oxysterol 7alpha-hydroxylase enzyme activity, mRNA, or protein levels cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O
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 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.29 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.29 liver enzyme is induced in the third week of life Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.29 cholest-5-ene-3beta,25-diol + NADPH + H+ + O2
-
 Mus musculus cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O
-
 ?
1.14.14.29 cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 dietary cholesterol or colestipol do not affect oxysterol 7alpha-hydroxylase enzyme activity, mRNA, or protein levels Mus musculus cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.29 CYP7B1
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 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.14.29 cytochrome P-450
-
 Mus musculus
1.14.14.29 NADPH
-
 Mus musculus