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Literature summary extracted from

  • Spencer, A.L.; Bagai, I.; Becker, D.F.; Zuiderweg, E.R.; Ragsdale, S.W.
    Protein/protein interactions in the mammalian heme degradation pathway: heme oxygenase-2, cytochrome P450 reductase, and biliverdin reductase (2014), J. Biol. Chem., 289, 29836-29858.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.3.1.24 expressed in Escherichia coli BL21(DE3)-RIL cells Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.3.1.24 33000
-
 x * 33000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.1.24 biliverdin + NADH + H+ Homo sapiens
-
 bilirubin + NAD+
-
 r
1.3.1.24 biliverdin + NADPH + H+ Homo sapiens
-
 bilirubin + NADP+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.24 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.1.24 glutathione-Sepharose column chromatography, and Superdex 200 gel filtration Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.24 biliverdin + NADH + H+
-
 Homo sapiens bilirubin + NAD+
-
 r
1.3.1.24 biliverdin + NADPH + H+
-
 Homo sapiens bilirubin + NADP+
-
 r

Subunits

EC Number Subunits Comment Organism
1.3.1.24 ? x * 33000, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
1.3.1.24 BVR
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.24 NADH
-
 Homo sapiens
1.3.1.24 NADPH
-
 Homo sapiens